Brain tissue is not only one of the most important but also the most complex and compliant
tissue in the human body. While long underestimated, increasing evidence confirms that …

Traumatic brain injury (TBI) is the most common cause of death and disability in those aged
under 40 years in the UK. Higher rates of morbidity and mortality are seen in low-income …

Background Traumatic acute subdural hematomas frequently warrant surgical evacuation by
means of a craniotomy (bone flap replaced) or decompressive craniectomy (bone flap not …

Background The effect of decompressive craniectomy on clinical outcomes in patients with
refractory traumatic intracranial hypertension remains unclear. Methods From 2004 through …

Subarachnoid haemorrhage is an uncommon and severe subtype of stroke affecting
patients at a mean age of 55 years, leading to loss of many years of productive life. The …

Traumatic brain injury (TBI) remains a significant source of death and permanent disability,
contributing to nearly one-third of all injury related deaths in the United States and exacting …

Importance Trials often assess primary outcomes of traumatic brain injury at 6 months.
Longer-term data are needed to assess outcomes for patients receiving surgical vs medical …

Traumatic brain injury (TBI) is a common disorder with high morbidity and mortality,
accounting for one in every three deaths due to injury. Older adults are especially …

Background Due to the lack of high-quality evidence which has hindered the development of
evidence-based guidelines, there is a need to provide general guidance on cranioplasty …

Decompressive craniectomy (DC) has become the definitive surgical procedure to manage
medically intractable rise in intracranial pressure due to stroke and traumatic brain injury …