A review of food–drug interactions on oral drug absorption
Food effect, also known as food–drug interactions, is a common phenomenon associated
with orally administered medications and can be defined as changes in absorption rate or …
with orally administered medications and can be defined as changes in absorption rate or …
Bioavailability and bioequivalence in drug development
SC Chow - Wiley Interdisciplinary Reviews: Computational …, 2014 - Wiley Online Library
Bioavailability is referred to as the extent and rate to which the active drug ingredient or
active moiety from the drug product is absorbed and becomes available at the site of drug …
active moiety from the drug product is absorbed and becomes available at the site of drug …
Bioavailability and bioequivalence: an FDA regulatory overview
ML Chen, V Shah, R Patnaik, W Adams… - Pharmaceutical …, 2001 - Springer
Bioavailability and/or bioequivalence studies play a key role in the drug development period
for both new drug products and their generic equivalents. For both, these studies are also …
for both new drug products and their generic equivalents. For both, these studies are also …
[HTML][HTML] Evaluation of excipient risk in BCS class I and III biowaivers
M Metry, JE Polli - The AAPS journal, 2022 - Springer
The objective of this review article is to summarize literature data pertinent to potential
excipient effects on intestinal drug permeability and transit. Despite the use of excipients in …
excipient effects on intestinal drug permeability and transit. Despite the use of excipients in …
Contrast medium dose-to-GFR ratio: a measure of systemic exposure to predict contrast-induced nephropathy after percutaneous coronary intervention
U Nyman, J Björk, P Aspelin, G Marenzi - Acta radiologica, 2008 - Taylor & Francis
Background: The contrast medium (CM) dose-to-eGFR (estimated glomerular filtration rate)
ratio has recently been advocated to express systemic exposure to CM in assessing the risk …
ratio has recently been advocated to express systemic exposure to CM in assessing the risk …
Preventing contrast medium-induced acute kidney injury: side-by-side comparison of Swedish-ESUR guidelines
A side-by-side comparison of updated guidelines regarding contrast medium-induced acute
kidney injury (CI-AKI) from the Swedish Society of Uroradiology (SSUR) and the European …
kidney injury (CI-AKI) from the Swedish Society of Uroradiology (SSUR) and the European …
[HTML][HTML] Are intravenous injections of contrast media really less nephrotoxic than intra-arterial injections?
U Nyman, T Almén, B Jacobsson, P Aspelin - European radiology, 2012 - Springer
We oppose the opinion that the intra-arterial administration of iodine-based contrast media
(CM) appears to pose a greater risk of contrast medium-induced nephropathy (CIN) than …
(CM) appears to pose a greater risk of contrast medium-induced nephropathy (CIN) than …
[HTML][HTML] Absolute and relative GFR and contrast medium dose/GFR ratio: cornerstones when predicting the risk of acute kidney injury
Glomerular filtration rate (GFR) is considered the best overall index of kidney function in
health and disease and its use is recommended to evaluate the risk of iodine contrast …
health and disease and its use is recommended to evaluate the risk of iodine contrast …
Influence of age and cytochrome P450 2C9 genotype on the steady-state disposition of diclofenac and celecoxib
SS Brenner, C Herrlinger, K Dilger, TE Mürdter… - Clinical …, 2003 - Springer
Objective To analyse the influence of age and cytochrome P450 (CYP) 2C9 genotype on the
steady-state disposition of the standard NSAID diclofenac and the new COX-2 selective …
steady-state disposition of the standard NSAID diclofenac and the new COX-2 selective …