Glucocorticoids are powerful regulators of immune function. Their role in reducing
inflammation and autoimmune responses is well known, as is their ability to induce …

Glucocorticoids have profound and complex effects on the human immune response.
However, the precise mechanisms of the corticosteroid-induced immunoregulation in man …

Objective To determine the frequency of prescriptions for short term use of oral
corticosteroids, and adverse events (sepsis, venous thromboembolism, fractures) associated …

Corticosteroids have been used for decades to modulate inflammation therapeutically, yet
there is a paucity of data on their effects in humans. We examined the changes in cellular …

Central nervous system (CNS) nocardiosis is a rare disease entity caused by the
filamentous bacteria Nocardia species. We present a case series of 5 patients from our …

Most clinicians know that emotional life experiences, such as bereavement, divorce, or loss
of employment, increase the probability of some type of illness. Pleasant postoperative …

Background: Bacterial infections remain important causes of morbidity and mortality in
surgical patients. Our understanding of the effects of bacteria on the host, and also the …

The ability to evaluate distress in laboratory animals is needed in order to ensure that
husbandry and experimental procedures do not negatively impact animal welfare. Accurate …

Glucocorticosteroid hormones affect virtually every tissue type in the body, including tissues
of host‐defense systems. There is an enormous body of literature concerning specific effects …

Publisher Summary It had been suggested that the autologous mixed-lymphocyte reaction
(MLR) might result from perturbations of the responding or stimulating cells during cell …