Vaccine adjuvants: mechanisms and platforms
T Zhao, Y Cai, Y Jiang, X He, Y Wei, Y Yu… - Signal transduction and …, 2023 - nature.com
Adjuvants are indispensable components of vaccines. Despite being widely used in
vaccines, their action mechanisms are not yet clear. With a greater understanding of the …
vaccines, their action mechanisms are not yet clear. With a greater understanding of the …
Chemical and biomolecular strategies for STING pathway activation in cancer immunotherapy
KM Garland, TL Sheehy, JT Wilson - Chemical reviews, 2022 - ACS Publications
The stimulator of interferon genes (STING) cellular signaling pathway is a promising target
for cancer immunotherapy. Activation of the intracellular STING protein triggers the …
for cancer immunotherapy. Activation of the intracellular STING protein triggers the …
Adjuvants for coronavirus vaccines
Z Liang, H Zhu, X Wang, B Jing, Z Li, X Xia… - Frontiers in …, 2020 - frontiersin.org
Vaccine development utilizing various platforms is one of the strategies that has been
proposed to address the coronavirus disease 2019 (COVID-19) pandemic. Adjuvants are …
proposed to address the coronavirus disease 2019 (COVID-19) pandemic. Adjuvants are …
Nanoparticle-based strategies to combat COVID-19
Coronavirus disease 2019 (COVID-19) is the worst pandemic disease of the current
millennium. This disease is caused by the highly contagious severe acute respiratory …
millennium. This disease is caused by the highly contagious severe acute respiratory …
[HTML][HTML] Delivery of STING agonists for adjuvanting subunit vaccines
Adjuvant is an essential component in subunit vaccines. Many agonists of pathogen
recognition receptors have been developed as potent adjuvants to optimize the …
recognition receptors have been developed as potent adjuvants to optimize the …
Structure‐based varieties of polymeric nanocarriers and influences of their physicochemical properties on drug delivery profiles
Carriers are equally important as drugs. They can substantially improve bioavailability of
cargos and safeguard healthy cells from toxic effects of certain therapeutics. Recently …
cargos and safeguard healthy cells from toxic effects of certain therapeutics. Recently …
Manganese coordination micelles that activate stimulator of interferon genes and capture in situ tumor antigens for cancer metalloimmunotherapy
J Li, H Ren, Q Qiu, X Yang, J Zhang, C Zhang, B Sun… - ACS …, 2022 - ACS Publications
Cancer immunotherapy holds great promise but is generally limited by insufficient induction
of anticancer immune responses. Here, a metal micellar nanovaccine is developed by the …
of anticancer immune responses. Here, a metal micellar nanovaccine is developed by the …
Application prospect of polysaccharides in the development of anti-novel coronavirus drugs and vaccines
X Chen, W Han, G Wang, X Zhao - International journal of biological …, 2020 - Elsevier
Since the outbreak of the novel coronavirus disease COVID-19, caused by the SARS-CoV-2
virus, it has spread rapidly worldwide and poses a great threat to public health. This is the …
virus, it has spread rapidly worldwide and poses a great threat to public health. This is the …
Nanoparticle-based drug delivery system: the magic bullet for the treatment of chronic pulmonary diseases
S Pramanik, S Mohanto, R Manne… - Molecular …, 2021 - ACS Publications
Chronic pulmonary diseases encompass different persistent and lethal diseases, including
chronic obstructive pulmonary disease (COPD), idiopathic pulmonary fibrosis (IPF), cystic …
chronic obstructive pulmonary disease (COPD), idiopathic pulmonary fibrosis (IPF), cystic …
Polymeric nanoparticle vaccines to combat emerging and pandemic threats
D Wibowo, SHT Jorritsma, ZJ Gonzaga, B Evert… - Biomaterials, 2021 - Elsevier
Subunit vaccines are more advantageous than live attenuated vaccines in terms of safety
and scale-up manufacture. However, this often comes as a trade-off to their efficacy. Over …
and scale-up manufacture. However, this often comes as a trade-off to their efficacy. Over …