Soy protein, bioactive peptides, and isoflavones: a review of their safety and health benefits.

ST Tan, SS Tan, CX Tan - PharmaNutrition, 2023 - Elsevier
Introduction Literature has consistently reported that soy and soy-based foods are excellent
sources of amino acids and isoflavones. Therefore, this review summarises the safety and …

Genetic backgrounds and diagnosis of familial hypercholesterolemia

J Rogozik, R Główczyńska, M Grabowski - Clinical Genetics, 2024 - Wiley Online Library
Lipid disorders play a critical role in the intricate development of atherosclerosis and its
clinical consequences, such as coronary heart disease and stroke. These disorders are …

Japan Atherosclerosis Society (JAS) guidelines for prevention of atherosclerotic cardiovascular diseases 2022

T Okamura, K Tsukamoto, H Arai, Y Fujioka… - … of Atherosclerosis and …, 2023 - jstage.jst.go.jp
In Japan, a super-aged society, deaths from atherosclerotic cardiovascular disease
(ASCVD), especially cardiac diseases including coronary artery disease (CAD) such as …

Multi-organ protective effects of sodium glucose cotransporter 2 inhibitors

H Yanai, M Hakoshima, H Adachi… - International Journal of …, 2021 - mdpi.com
Sodium glucose cotransporter 2 inhibitors (SGLT2i) block the reabsorption of glucose by
inhibiting SGLT2, thus improving glucose control by promoting the renal excretion of …

Urate transporter 1 can be a therapeutic target molecule for chronic kidney disease and diabetic kidney disease: a retrospective longitudinal study

H Yanai, H Katsuyama, M Hakoshima, H Adachi - Biomedicines, 2023 - mdpi.com
Chronic kidney disease (CKD) is a major global health problem for which there are no
curative drug treatments. Hyperuricemia is one of risk factors for CKD. The evidence on …

[HTML][HTML] Novel dietary intervention program “COMB meal program” approaching health and presenteeism: Two pilot studies

T Nakazeko, N Shobako, Y Hirano, F Nakamura… - Journal of Functional …, 2022 - Elsevier
Presenteeism is a major issue faced by workplaces around the world. While nutritional
education has been well studied for its resolution, few studies have reported its …

Present and future of dyslipidaemia treatment—a review

I Merćep, A Vujević, D Strikić, I Radman, I Pećin… - Journal of Clinical …, 2023 - mdpi.com
One of the greatest burdens on the healthcare systems of modern civilization is
cardiovascular diseases (CVDs). Therefore, the medical community is looking for ways to …

Omega-3 (n-3) Fatty Acid–Statin Interaction: Evidence for a Novel Therapeutic Strategy for Atherosclerotic Cardiovascular Disease

I Djuricic, PC Calder - Nutrients, 2024 - mdpi.com
Managing atherosclerotic cardiovascular disease (ASCVD) often involves a combination of
lifestyle modifications and medications aiming to decrease the risk of cardiovascular …

Lipid disorders and metabolic-associated fatty liver disease

SD Anwar, C Foster, A Ashraf - Endocrinology and Metabolism …, 2023 - endo.theclinics.com
Metabolic-associated fatty liver disease (MAFLD) is now considered the most frequent cause
of chronic liver disease in the world because of the alarming rise in obesity across the globe …

Pharmacological modulation of cholesterol 7α-hydroxylase (CYP7A1) as a therapeutic strategy for hypercholesterolemia

MYC Lim, HK Ho - Biochemical Pharmacology, 2023 - Elsevier
Despite the availability of many therapeutic options, the prevalence of hypercholesterolemia
remains high. There exists a significant unmet medical need for novel drugs and/or …