Fixed-dose combination therapies with and without aspirin for primary prevention of cardiovascular disease: an individual participant data meta-analysis

P Joseph, G Roshandel, P Gao, P Pais, E Lonn… - The Lancet, 2021 - thelancet.com
Background In randomised controlled trials, fixed-dose combination treatments (or polypills)
have been shown to reduce a composite of cardiovascular disease outcomes in primary …

Elevated remnant cholesterol, plasma triglycerides, and cardiovascular and non-cardiovascular mortality

BN Wadström, KM Pedersen, AB Wulff… - European heart …, 2023 - academic.oup.com
Aims Cholesterol carried in triglyceride-rich lipoproteins, also called remnant cholesterol, is
being increasingly acknowledged as an important causal risk factor for atherosclerosis …

Sex differences in peripheral artery disease

M Pabon, S Cheng, SE Altin, SS Sethi… - Circulation …, 2022 - Am Heart Assoc
Peripheral artery disease (PAD) is a prevalent condition that confers substantial morbidity
and mortality and remains underdiagnosed as well as undertreated in the overall …

Global, regional, and national time trends in mortality for congenital heart disease, 1990–2019: An age-period-cohort analysis for the Global Burden of Disease 2019 …

Z Su, Z Zou, SI Hay, Y Liu, S Li, H Chen… - …, 2022 - thelancet.com
Background Congenital heart disease (CHD) is the leading cause of morbidity and mortality
from birth defects worldwide. We report an overview of trends in CHD mortality in 204 …

Extracellular vesicles as tools and targets in therapy for diseases

MA Kumar, SK Baba, HQ Sadida… - Signal transduction and …, 2024 - nature.com
Extracellular vesicles (EVs) are nano-sized, membranous structures secreted into the
extracellular space. They exhibit diverse sizes, contents, and surface markers and are …

The global syndemic of metabolic diseases in the young adult population: A consortium of trends and projections from the Global Burden of Disease 2000–2019

B Chong, G Kong, K Shankar, HSJ Chew, C Lin, R Goh… - Metabolism, 2023 - Elsevier
Background A significant proportion of premature deaths globally are related to metabolic
diseases in young adults. We examined the global trends and mortality of metabolic …

[HTML][HTML] Game changers in science and technology-now and beyond

UAK Betz, L Arora, RA Assal, H Azevedo… - … Forecasting and Social …, 2023 - Elsevier
The recent devastating pandemic has drastically reminded humanity of the importance of
constant scientific and technological progress. A strong interdisciplinary dialogue between …

Artificial intelligence in medicine

P Hamet, J Tremblay - metabolism, 2017 - Elsevier
Artificial Intelligence (AI) is a general term that implies the use of a computer to model
intelligent behavior with minimal human intervention. AI is generally accepted as having …

Efficacy of a digital therapeutics system in the management of essential hypertension: the HERB-DH1 pivotal trial

K Kario, A Nomura, N Harada, A Okura… - European heart …, 2021 - academic.oup.com
Aims Digital therapeutics is a new approach to facilitate the non-pharmacological treatment
of hypertension using software programmes such as smartphone applications and/or device …

Plant-based dietary patterns for human and planetary health

J Gibbs, FP Cappuccio - Nutrients, 2022 - mdpi.com
The coronavirus pandemic has acted as a reset on global economies, providing us with the
opportunity to build back greener and ensure global warming does not surpass 1.5° C. It is …