[HTML][HTML] Guidelines and recommendations on yeast cell death nomenclature
Elucidating the biology of yeast in its full complexity has major implications for science,
medicine and industry. One of the most critical processes determining yeast life and …
medicine and industry. One of the most critical processes determining yeast life and …
Apoptosis in yeast: triggers, pathways, subroutines
A cell's decision to die is controlled by a sophisticated network whose deregulation
contributes to the pathogenesis of multiple diseases including neoplastic and …
contributes to the pathogenesis of multiple diseases including neoplastic and …
Cdc48: a power machine in protein degradation
A Stolz, W Hilt, A Buchberger, DH Wolf - Trends in biochemical sciences, 2011 - cell.com
Cdc48 is an essential, highly prominent ATP driven machine in eukaryotic cells.
Physiological function of Cdc48 has been found in a multitude of cellular processes, for …
Physiological function of Cdc48 has been found in a multitude of cellular processes, for …
[HTML][HTML] Recent advances in p97/VCP/Cdc48 cellular functions
K Yamanaka, Y Sasagawa, T Ogura - Biochimica et Biophysica Acta (BBA) …, 2012 - Elsevier
p97/VCP/Cdc48 is one of the best-characterized type II AAA (ATPases associated with
diverse cellular activities) ATPases. p97 is suggested to be a ubiquitin-selective chaperone …
diverse cellular activities) ATPases. p97 is suggested to be a ubiquitin-selective chaperone …
Critical role of proteostasis-imbalance in pathogenesis of COPD and severe emphysema
T Min, M Bodas, S Mazur, N Vij - Journal of molecular medicine, 2011 - Springer
The environmental, genetic, and/or age-related changes in proteostasis induce
inflammation, oxidative stress, and apoptosis. We quantified the correlation of protein …
inflammation, oxidative stress, and apoptosis. We quantified the correlation of protein …
New insights into the role of sequestosome 1/p62 mutant proteins in the pathogenesis of Paget's disease of bone
SL Rea, JP Walsh, R Layfield, T Ratajczak… - Endocrine …, 2013 - academic.oup.com
Paget's disease of bone (PDB) is characterized by focal areas of aberrant and excessive
bone turnover, specifically increased bone resorption and disorganized bone formation …
bone turnover, specifically increased bone resorption and disorganized bone formation …
Peptides and combination of peptides for use in immunotherapy against small cell lung cancer and other cancers
M Andrea, T Weinschenk, V Goldfinger… - US Patent …, 2019 - Google Patents
The present invention relates to peptides, proteins, nucleic acids and cells for use in
immunotherapeutic methods. In particular, the present invention relates to the immuno …
immunotherapeutic methods. In particular, the present invention relates to the immuno …
Peptides and combination of peptides for use in immunotherapy against small cell lung cancer and other cancers
A Mahr, T Weinschenk, V Goldfinger, O Schoor… - 2018 - Google Patents
ZRKFYGHZFMAOKI-QMGMOQQFSA-N tgfbeta Chemical compound C ([C@ H](NC (=
O)[C@ H](C (C) C) NC (= O) CNC (= O)[C@ H](CCC (O)= O) NC (= O)[C@ H](CCCNC (N) …
O)[C@ H](C (C) C) NC (= O) CNC (= O)[C@ H](CCC (O)= O) NC (= O)[C@ H](CCCNC (N) …
Lysine methylation of VCP by a member of a novel human protein methyltransferase family
S Kernstock, E Davydova, M Jakobsson, A Moen… - Nature …, 2012 - nature.com
Valosin-containing protein (VCP, also called p97) is an essential and highly conserved
adenosine triphosphate-dependent chaperone implicated in a wide range of cellular …
adenosine triphosphate-dependent chaperone implicated in a wide range of cellular …
Inhibitors of the AAA+ chaperone p97
E Chapman, N Maksim, F De la Cruz, JJ La Clair - Molecules, 2015 - mdpi.com
It is remarkable that a pathway as ubiquitous as protein quality control can be targeted to
treat cancer. Bortezomib, an inhibitor of the proteasome, was first approved by the US Food …
treat cancer. Bortezomib, an inhibitor of the proteasome, was first approved by the US Food …