The fibrotic process could be easily defined as a pathological excess of extracellular matrix
deposition, leading to disruption of tissue architecture and eventually loss of function; …

Interstitial lung diseases (ILDs) are a heterogeneous group of diseases characterized by
varying degrees of inflammation and fibrosis of the pulmonary interstitium. The interrelations …

Idiopathic pulmonary fibrosis (IPF) is characterized by an aberrant repair response with
uncontrolled turnover of extracellular matrix involving mesenchymal cell phenotypes, where …

Herein, we investigate the combinatorial therapeutic effects of naturally occurring flavonoids
kaempferol (K) and fisetin (F) on triple-negative breast cancer (TNBC: MDA-MB-231 cell …

Chronic kidney disease (CKD) predisposes one toward end-stage renal disease (ESRD)
and its associated morbidity and mortality. Significant metabolic perturbations in conjunction …

Chronic exposure to arsenic in drinking water damages cognitive function, and nerve cell
apoptosis is one of the primary characteristics. The damage to mitochondrial structure and/or …

Cardiovascular diseases caused by atherosclerosis (AS) seriously endanger human health,
which is closely related to vascular smooth muscle cell (VSMC) phenotypes. VSMC …

Highlights What are the main findings? We reviewed the latest advances in aberrant
molecular events and pathological alterations in different cell populations in idiopathic …

Idiopathic pulmonary fibrosis (IPF) presents as an incurable change in the lung tissue and
mitochondrial dysfunction of unknown origin. Treprostinil, a prostacyclin analogue, has been …

Particulate matter with aerodynamic diameter not larger than 2.5 μm (PM 2.5) escalated the
risk of respiratory diseases. Mitochondrial dysfunction may play a pivotal role in PM 2.5 …