Neuroprotection during Thrombectomy for Acute Ischemic Stroke: A Review of Future Therapies

V Dammavalam, S Lin, S Nessa, N Daksla… - International Journal of …, 2024 - mdpi.com
Stroke is a major cause of death and disability worldwide. Endovascular thrombectomy has
been impactful in decreasing mortality. However, many clinical results continue to show …

[PDF][PDF] Dihydromyricetin attenuates cerebral ischemia reperfusion injury by inhibiting SPHK1/mTOR signaling and targeting ferroptosis

J Xie, T Zhang, P Li, D Wang, T Liu… - Drug design, development …, 2022 - Taylor & Francis
Background Dihydromyricetin (DHM) exerts protective effects in various brain diseases. The
aim of this research was to investigate the biological role of DHM in cerebral ischemia …

Effect of remote ischemic conditioning on the immune-inflammatory profile in patients with traumatic hemorrhagic shock in a randomized controlled trial

CH Leung, SB Rizoli, S Trypcic, SG Rhind… - Scientific Reports, 2023 - nature.com
Resuscitation induced ischemia/reperfusion predisposes trauma patients to systemic
inflammation and organ dysfunction. We investigated the effect of remote ischemic …

Current advances and future trends of hormesis in disease

Y Wan, J Liu, Y Mai, Y Hong, Z Jia, G Tian, Y Liu… - npj Aging, 2024 - nature.com
Hormesis, an adaptive response, occurs when exposure to low doses of a stressor
potentially induces a stimulatory effect, while higher doses may inhibit it. This phenomenon …

Safety and efficacy of remote ischemic conditioning combined with intravenous thrombolysis for acute ischemic stroke: a multicenter, randomized, parallel-controlled …

R Abuduxukuer, ZN Guo, P Zhang… - … Journal of Stroke, 2023 - journals.sagepub.com
Rationale: Remote ischemic conditioning (RIC) combined with intravenous thrombolysis
(IVT) may improve functional outcomes in patients with acute ischemic stroke (AIS). Aim: To …

A novel NIR-II albumin-escaping probe for cerebral arteries and perfusion imaging in stroke mice model

YY Sun, HJ Zhu, Y Du, S Zhu, SY Zhou, SY Pang, Y Qu… - Biomaterials, 2024 - Elsevier
In order to guide the formulation of post-stroke treatment strategy in time, it is necessary to
have real-time feedback on collateral circulation and revascularization. Currently used near …

Isoflurane anesthesia's impact on gene expression patterns of rat brains in an ischemic stroke model

YY Shpetko, IB Filippenkov, AE Denisova… - Genes, 2023 - mdpi.com
Background: Ischemic stroke (IS) is one of the most severe brain diseases. Animal models
with anesthesia are actively used to study stroke genomics and pathogenesis. However, the …

Neuroadaptive Biochemical Mechanisms of Remote Ischemic Conditioning

K Baranova, N Nalivaeva, E Rybnikova - International Journal of …, 2023 - mdpi.com
This review summarizes the currently known biochemical neuroadaptive mechanisms of
remote ischemic conditioning. In particular, it focuses on the significance of the pro-adaptive …

Role of Neuroprotective Approaches in the Recanalization Era

M Tymianski - Stroke, 2024 - Am Heart Assoc
Although thrombolysis, EVT, or both are a definitive treatment for AIS, too often, the extent of
reperfusion is incomplete or delayed, permitting ischemic damage to progress even in …

Effect of remote ischemic preconditioning in patients undergoing laparoscopic colorectal cancer surgery: a randomized controlled trial

X Yang, C Tian, Y Gao, L Yang, Y Wu… - Scandinavian Journal of …, 2023 - Taylor & Francis
Background Remote ischemic preconditioning (RIPC) is reported to reduce ischemia-
reperfusion injury (IRI) in many vital organs by inhibiting a systemic inflammatory response …