[HTML][HTML] Prostate cancer genetic risk and associated aggressive disease in men of African ancestry
PXY Soh, N Mmekwa, DC Petersen, K Gheybi… - Nature …, 2023 - nature.com
African ancestry is a significant risk factor for prostate cancer and advanced disease. Yet,
genetic studies have largely been conducted outside the context of Sub-Saharan Africa …
genetic studies have largely been conducted outside the context of Sub-Saharan Africa …
[HTML][HTML] Linking African ancestral substructure to prostate cancer health disparities
Prostate cancer (PCa) is a significant health burden in Sub-Saharan Africa, with mortality
rates loosely linked to African ancestry. Yet studies aimed at identifying contributing risk …
rates loosely linked to African ancestry. Yet studies aimed at identifying contributing risk …
Cancer genetic mutation prevalence in sub-Saharan Africa: A review of existing data
J Shain, A Michel, MS May, L Qunaj, W El-Sadr… - Seminars in …, 2023 - Elsevier
Background Cancer represents a leading cause of death worldwide. Germline mutations in
several genes increase the risk of developing several cancers, including cancers of the …
several genes increase the risk of developing several cancers, including cancers of the …
[HTML][HTML] Alterations in the epigenetic machinery associated with prostate cancer health disparities
J Craddock, J Jiang, SM Patrick, SBA Mutambirwa… - Cancers, 2023 - mdpi.com
Simple Summary African ancestry is a significant risk factor for aggressive prostate cancer
(PCa), with southern African ethnicity conferring a nearly 3-fold increased global risk for …
(PCa), with southern African ethnicity conferring a nearly 3-fold increased global risk for …
[HTML][HTML] The impact of telomere length on prostate cancer aggressiveness, genomic instability and health disparities
R Huang, MSR Bornman, PD Stricker, I Simoni Brum… - Scientific Reports, 2024 - nature.com
The telomere repetitive TTAGGG motif at the ends of chromosomes, serves to preserve
genomic integrity and chromosomal stability. In turn, genomic instability is a hallmark of …
genomic integrity and chromosomal stability. In turn, genomic instability is a hallmark of …
Common genetic variants associated with prostate cancer risk: the need for African inclusion
PXY Soh, VM Hayes - European urology, 2023 - pubmed.ncbi.nlm.nih.gov
Common Genetic Variants Associated with Prostate Cancer Risk: The Need for African
Inclusion Common Genetic Variants Associated with Prostate Cancer Risk: The Need for …
Inclusion Common Genetic Variants Associated with Prostate Cancer Risk: The Need for …
[HTML][HTML] A Comparison of 68Ga-PSMA PET/CT-Based Split Renal Function with 99mTc-MAG3 Renography in Patients with Metastatic Castration-Resistant Prostate Carcinoma …
L Gabela, T Mkhize, B Hadebe, L Harry, T Nxasana… - Diagnostics, 2024 - mdpi.com
Background: Physiological PSMA expression in the cells of the proximal renal tubules and
consecutive radiopharmaceutical binding and retention could potentially lead to radioligand …
consecutive radiopharmaceutical binding and retention could potentially lead to radioligand …