A review of cell-based computational modeling in cancer biology

J Metzcar, Y Wang, R Heiland… - JCO clinical cancer …, 2019 - ascopubs.org
Cancer biology involves complex, dynamic interactions between cancer cells and their
tissue microenvironments. Single-cell effects are critical drivers of clinical progression …

Mechanics of 3D cell–hydrogel interactions: experiments, models, and mechanisms

FJ Vernerey, S Lalitha Sridhar, A Muralidharan… - Chemical …, 2021 - ACS Publications
Hydrogels are highly water-swollen molecular networks that are ideal platforms to create
tissue mimetics owing to their vast and tunable properties. As such, hydrogels are promising …

[图书][B] The mathematics and mechanics of biological growth

A Goriely - 2017 - books.google.com
This monograph presents a general mathematical theory for biological growth. It provides
both a conceptual and a technical foundation for the understanding and analysis of …

[HTML][HTML] Nanoparticle-mediated cancer cell therapy: Basic science to clinical applications

J Verma, C Warsame, RK Seenivasagam… - Cancer and Metastasis …, 2023 - Springer
Every sixth person in the world dies due to cancer, making it the second leading severe
cause of death after cardiovascular diseases. According to WHO, cancer claimed nearly 10 …

Three-dimensional in vitro tumor models for cancer research and drug evaluation

X Xu, MC Farach-Carson, X Jia - Biotechnology advances, 2014 - Elsevier
Cancer occurs when cells acquire genomic instability and inflammation, produce abnormal
levels of epigenetic factors/proteins and tumor suppressors, reprogram the energy …

[HTML][HTML] Simulating tissue mechanics with agent-based models: concepts, perspectives and some novel results

P Van Liedekerke, MM Palm, N Jagiella… - Computational particle …, 2015 - Springer
In this paper we present an overview of agent-based models that are used to simulate
mechanical and physiological phenomena in cells and tissues, and we discuss underlying …

Multi-scale modeling of tissues using CompuCell3D

MH Swat, GL Thomas, JM Belmonte, A Shirinifard… - Methods in cell …, 2012 - Elsevier
The study of how cells interact to produce tissue development, homeostasis, or diseases
was, until recently, almost purely experimental. Now, multi-cell computer simulation …

In vivo fluorescence imaging in the second near-infrared window with long circulating carbon nanotubes capable of ultrahigh tumor uptake

JT Robinson, G Hong, Y Liang, B Zhang… - Journal of the …, 2012 - ACS Publications
Cancer imaging requires selective high accumulation of contrast agents in the tumor region
and correspondingly low uptake in healthy tissues. Here, by making use of a novel synthetic …

[HTML][HTML] Comparing individual-based approaches to modelling the self-organization of multicellular tissues

JM Osborne, AG Fletcher, JM Pitt-Francis… - PLoS computational …, 2017 - journals.plos.org
The coordinated behaviour of populations of cells plays a central role in tissue growth and
renewal. Cells react to their microenvironment by modulating processes such as movement …

[图书][B] Mathematical modeling of biological pattern formation

A Deutsch, S Dormann - 2005 - Springer
In this chapter we have presented mathematical modeling approaches to biological pattern
formation. While reaction-diffusion models are appropriate to describe the spatio-temporal …