Insights to SARS-CoV-2 life cycle, pathophysiology, and rationalized treatments that target COVID-19 clinical complications
Background Gaining further insights into SARS-CoV-2 routes of infection and the underlying
pathobiology of COVID-19 will support the design of rational treatments targeting the life …
pathobiology of COVID-19 will support the design of rational treatments targeting the life …
COVID-19-related mortality risk in people with severe mental illness: a systematic and critical review
M De Hert, V Mazereel, M Stroobants… - Frontiers in …, 2022 - frontiersin.org
Background: Increasing clinical evidence suggests that people with severe mental illness
(SMI), including schizophrenia spectrum disorders, bipolar disorder (BD), and major …
(SMI), including schizophrenia spectrum disorders, bipolar disorder (BD), and major …
SARS-CoV-2 infects cells after viral entry via clathrin-mediated endocytosis
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of
COVID-19, so understanding its biology and infection mechanisms is critical to facing this …
COVID-19, so understanding its biology and infection mechanisms is critical to facing this …
Repurposing sigma-1 receptor ligands for COVID-19 therapy?
JM Vela - Frontiers in Pharmacology, 2020 - frontiersin.org
Outbreaks of emerging infections, such as COVID-19 pandemic especially, confront health
professionals with the unique challenge of treating patients. With no time to discover new …
professionals with the unique challenge of treating patients. With no time to discover new …
Sleep dysfunction in COVID-19 patients: prevalence, risk factors, mechanisms, and management
A Pataka, S Kotoulas, E Sakka, P Katsaounou… - Journal of Personalized …, 2021 - mdpi.com
During the COVID-19 pandemic, the need to establish the prevalence of sleep dysfunction
and psychological distress, identify predisposing and protective factors, and explore …
and psychological distress, identify predisposing and protective factors, and explore …
Long COVID, neuropsychiatric disorders, psychotropics, present and future
SW Tang, BE Leonard, DM Helmeste - Acta neuropsychiatrica, 2022 - cambridge.org
Long COVID refers to the lingering symptoms which persist or appear after the acute illness.
The dominant long COVID symptoms in the two years since the pandemic began (2020 …
The dominant long COVID symptoms in the two years since the pandemic began (2020 …
Association between the use of psychotropic medications and the risk of COVID-19 infection among long-term inpatients with serious mental illness in a New York …
K Nemani, SZ Williams, M Olfson… - JAMA Network …, 2022 - jamanetwork.com
Importance Individuals with serious mental illness are at increased risk of severe COVID-19
infection. Several psychotropic medications have been identified as potential therapeutic …
infection. Several psychotropic medications have been identified as potential therapeutic …
The current landscape of coronavirus-host protein–protein interactions
L Perrin-Cocon, O Diaz, C Jacquemin, V Barthel… - Journal of translational …, 2020 - Springer
In less than 20 years, three deadly coronaviruses, SARS-CoV, MERS-CoV and SARS-CoV-
2, have emerged in human population causing hundreds to hundreds of thousands of …
2, have emerged in human population causing hundreds to hundreds of thousands of …
Antidepressant and Antipsychotic Drugs Reduce Viral Infection by SARS-CoV-2 and Fluoxetine Shows Antiviral Activity Against the Novel Variants in vitro
Repurposing of currently available drugs is a valuable strategy to tackle the consequences
of COVID-19. Recently, several studies have investigated the effect of psychoactive drugs on …
of COVID-19. Recently, several studies have investigated the effect of psychoactive drugs on …
Short linear motif candidates in the cell entry system used by SARS-CoV-2 and their potential therapeutic implications
B Mészáros, H Sámano-Sánchez… - Science …, 2021 - science.org
The first reported receptor for SARS-CoV-2 on host cells was the angiotensin-converting
enzyme 2 (ACE2). However, the viral spike protein also has an RGD motif, suggesting that …
enzyme 2 (ACE2). However, the viral spike protein also has an RGD motif, suggesting that …