Background Gaining further insights into SARS-CoV-2 routes of infection and the underlying
pathobiology of COVID-19 will support the design of rational treatments targeting the life …

Background: Increasing clinical evidence suggests that people with severe mental illness
(SMI), including schizophrenia spectrum disorders, bipolar disorder (BD), and major …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of
COVID-19, so understanding its biology and infection mechanisms is critical to facing this …

Outbreaks of emerging infections, such as COVID-19 pandemic especially, confront health
professionals with the unique challenge of treating patients. With no time to discover new …

During the COVID-19 pandemic, the need to establish the prevalence of sleep dysfunction
and psychological distress, identify predisposing and protective factors, and explore …

Long COVID refers to the lingering symptoms which persist or appear after the acute illness.
The dominant long COVID symptoms in the two years since the pandemic began (2020 …

Importance Individuals with serious mental illness are at increased risk of severe COVID-19
infection. Several psychotropic medications have been identified as potential therapeutic …

In less than 20 years, three deadly coronaviruses, SARS-CoV, MERS-CoV and SARS-CoV-
2, have emerged in human population causing hundreds to hundreds of thousands of …

Repurposing of currently available drugs is a valuable strategy to tackle the consequences
of COVID-19. Recently, several studies have investigated the effect of psychoactive drugs on …

The first reported receptor for SARS-CoV-2 on host cells was the angiotensin-converting
enzyme 2 (ACE2). However, the viral spike protein also has an RGD motif, suggesting that …