The role of flavonoids in autoimmune diseases: Therapeutic updates

KRR Rengasamy, H Khan, S Gowrishankar… - Pharmacology & …, 2019 - Elsevier
Flavonoids are natural polyphenolic compounds which are included in a panoply of drugs
and used to treat and/or manage human ailments such as metabolic, cardiovascular …

The interplay between tuberculosis and systemic lupus erythematosus

GGM Balbi, F Machado-Ribeiro… - Current Opinion in …, 2018 - journals.lww.com
We reviewed the most relevant aspects of TB infection in SLE patients, including the burden
of TB, its role in inducing flare and its perpetuation, risk evaluation and prevention, and …

Safety and efficacy of belimumab to treat systemic lupus erythematosus in academic clinical practices

JS Hui-Yuen, A Reddy, J Taylor, X Li… - The Journal of …, 2015 - jrheum.org
Objective. To evaluate the use and efficacy of belimumab in academic practices. Belimumab
is a human monoclonal antibody that inhibits soluble B lymphocyte stimulator and has been …

[HTML][HTML] First real-world insights into belimumab use and outcomes in routine clinical care of systemic lupus erythematosus in Germany: results from the OBSErve …

A Schwarting, JO Schroeder, T Alexander… - Rheumatology and …, 2016 - Springer
OBSErve Germany was the first observational study of belimumab as add-on treatment for
systemic lupus erythematosus (SLE) in routine clinical care in Germany, retrospectively …

Belimumab for the treatment of recalcitrant cutaneous lupus

P Vashisht, K Borghoff, JR O'Dell, M Hearth-Holmes - Lupus, 2017 - journals.sagepub.com
Background Belimumab is a monoclonal antibody that reduces B lymphocyte survival by
blocking the binding of soluble human B lymphocyte stimulator (BLyS) to its B cell receptors …

[HTML][HTML] Recent advances in the management of systemic lupus erythematosus

S Sciascia, M Radin, D Roccatello, G Sanna… - …, 2018 - ncbi.nlm.nih.gov
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease presenting highly
heterogeneous clinical manifestations and multi-systemic involvement. Patients are …

Current and emerging treatment options for ANCA-associated vasculitis: potential role of belimumab and other BAFF/APRIL targeting agents

A Lenert, P Lenert - Drug design, development and therapy, 2015 - Taylor & Francis
Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) comprises several
clinical entities with diverse clinical presentations, outcomes, and nonunifying pathogenesis …

Belimumab in systemic lupus erythematosus (SLE): evidence-to-date and clinical usefulness

S Guerreiro Castro… - Therapeutic advances in …, 2017 - journals.sagepub.com
Systemic lupus erythematosus (SLE) is a complex autoimmune rheumatic disease with
multiple presentations, whose management presents many challenges. Many disease …

Spotlight on blisibimod and its potential in the treatment of systemic lupus erythematosus: evidence to date

A Lenert, TB Niewold, P Lenert - Drug Design, Development and …, 2017 - Taylor & Francis
B cells in general and BAFF (B cell activating factor of the tumor necrosis factor [TNF] family)
in particular have been primary targets of recent clinical trials in systemic lupus …

Belimumab for the treatment of corticosteroid-dependent systemic lupus erythematosus: from clinical trials to real-life experience after 1 year of use in 48 Brazilian …

M Scheinberg, FFN de Melo, AN Bueno, CM Costa… - Clinical …, 2016 - Springer
The objective of the study was to evaluate prospectively real-life experience on the effect of
belimumab on patients with active systemic lupus erythematosus (SLE). Forty-eight patients …