Dopamine: the neuromodulator of long-term synaptic plasticity, reward and movement control
L Speranza, U Di Porzio, D Viggiano, A de Donato… - Cells, 2021 - mdpi.com
Dopamine (DA) is a key neurotransmitter involved in multiple physiological functions
including motor control, modulation of affective and emotional states, reward mechanisms …
including motor control, modulation of affective and emotional states, reward mechanisms …
Biological sequence classification: A review on data and general methods
C Ao, S Jiao, Y Wang, L Yu, Q Zou - Research, 2022 - spj.science.org
With the rapid development of biotechnology, the number of biological sequences has
grown exponentially. The continuous expansion of biological sequence data promotes the …
grown exponentially. The continuous expansion of biological sequence data promotes the …
[HTML][HTML] A high-resolution transcriptomic and spatial atlas of cell types in the whole mouse brain
The mammalian brain consists of millions to billions of cells that are organized into many cell
types with specific spatial distribution patterns and structural and functional properties …
types with specific spatial distribution patterns and structural and functional properties …
Single-cell genomic profiling of human dopamine neurons identifies a population that selectively degenerates in Parkinson's disease
T Kamath, A Abdulraouf, SJ Burris, J Langlieb… - Nature …, 2022 - nature.com
The loss of dopamine (DA) neurons within the substantia nigra pars compacta (SNpc) is a
defining pathological hallmark of Parkinson's disease (PD). Nevertheless, the molecular …
defining pathological hallmark of Parkinson's disease (PD). Nevertheless, the molecular …
The connectome of the adult Drosophila mushroom body provides insights into function
Making inferences about the computations performed by neuronal circuits from synapse-
level connectivity maps is an emerging opportunity in neuroscience. The mushroom body …
level connectivity maps is an emerging opportunity in neuroscience. The mushroom body …
Unique functional responses differentially map onto genetic subtypes of dopamine neurons
Dopamine neurons are characterized by their response to unexpected rewards, but they
also fire during movement and aversive stimuli. Dopamine neuron diversity has been …
also fire during movement and aversive stimuli. Dopamine neuron diversity has been …
[HTML][HTML] Biphasic activation of WNT signaling facilitates the derivation of midbrain dopamine neurons from hESCs for translational use
Human pluripotent stem cells show considerable promise for applications in regenerative
medicine, including the development of cell replacement paradigms for the treatment of …
medicine, including the development of cell replacement paradigms for the treatment of …
State and rate-of-change encoding in parallel mesoaccumbal dopamine pathways
The nervous system uses fast-and slow-adapting sensory detectors in parallel to enable
neuronal representations of external states and their temporal dynamics. It is unknown …
neuronal representations of external states and their temporal dynamics. It is unknown …
The role of neurod genes in brain development, function, and disease
S Tutukova, V Tarabykin… - Frontiers in Molecular …, 2021 - frontiersin.org
Transcriptional regulation is essential for the correct functioning of cells during development
and in postnatal life. The basic Helix-loop-Helix (bHLH) superfamily of transcription factors is …
and in postnatal life. The basic Helix-loop-Helix (bHLH) superfamily of transcription factors is …
Synaptic and circuit functions of multitransmitter neurons in the mammalian brain
ML Wallace, BL Sabatini - Neuron, 2023 - cell.com
Neurons in the mammalian brain are not limited to releasing a single neurotransmitter but
often release multiple neurotransmitters onto postsynaptic cells. Here, we review recent …
often release multiple neurotransmitters onto postsynaptic cells. Here, we review recent …