Hypoxia-targeted drug delivery

A Sharma, JF Arambula, S Koo, R Kumar… - Chemical Society …, 2019 - pubs.rsc.org
Hypoxia is a state of low oxygen tension found in numerous solid tumours. It is typically
associated with abnormal vasculature, which results in a reduced supply of oxygen and …

Biopolymer poly-hydroxyalkanoates (PHA) production from apple industrial waste residues: A review

H Liu, V Kumar, L Jia, S Sarsaiya, D Kumar, A Juneja… - Chemosphere, 2021 - Elsevier
Apple pomace, the residue which is left out after processing of apple serves as a potential
carbon source for the production of biopolymer, PHA (poly-hydroxyalkanoates). It is rich in …

Recent advances in emulsion-based delivery approaches for curcumin: From encapsulation to bioaccessibility

A Araiza-Calahorra, M Akhtar, A Sarkar - Trends in Food Science & …, 2018 - Elsevier
Background Curcumin has been widely acknowledged for its health-promoting effects.
However, its application is often limited by its poor water solubility and biochemical/structural …

Curcumin delivery mediated by bio-based nanoparticles: a review

M Moballegh Nasery, B Abadi, D Poormoghadam… - Molecules, 2020 - mdpi.com
Todays, nano-pharmaceutics is emerging as an important field of science to develop and
improve efficacy of different drugs. Although nutraceuticals are currently being utilized in the …

Therapeutic applications of curcumin nanoformulations

MM Yallapu, PKB Nagesh, M Jaggi, SC Chauhan - The AAPS journal, 2015 - Springer
Curcumin (diferuloylmethane) is a bioactive and major phenolic component of turmeric
derived from the rhizomes of curcuma longa linn. For centuries, curcumin has exhibited …

Exosomes for the enhanced tissue bioavailability and efficacy of curcumin

F Aqil, R Munagala, J Jeyabalan, AK Agrawal… - The AAPS journal, 2017 - Springer
Exosomes are extracellular microvesicles with a particle size of 30–100 nm and carry a
cargo of proteins, lipids, RNA, and DNA. Their properties of shuttling in-and-out of the cells …

Bacterial polyhydroxyalkanoates-eco-friendly next generation plastic: production, biocompatibility, biodegradation, physical properties and applications

Muhammadi, Shabina, M Afzal… - Green Chemistry Letters …, 2015 - Taylor & Francis
Polyhydroxyalkanoates (PHAs) are intracellular aliphatic polyesters synthesized as energy
reserves, in the form of water-insoluble, nano-sized discrete and optically dense granules in …

Application of nanotechnology in improving bioavailability and bioactivity of diet-derived phytochemicals

S Wang, R Su, S Nie, M Sun, J Zhang, D Wu… - The Journal of nutritional …, 2014 - Elsevier
Nanotechnology is an innovative approach that has potential applications in nutraceutical
research. Phytochemicals have promising potential for maintaining and promoting health, as …

Amino acid coordination driven self‐assembly for enhancing both the biological stability and tumor accumulation of curcumin

Y Li, Q Zou, C Yuan, S Li, R Xing… - Angewandte Chemie …, 2018 - Wiley Online Library
Clinical translation of curcumin has been highly obstructed by the rapid degradation and
poor tissue absorption of this agent. Herein, we report on the generation of supramolecular …

Curcumin nanoformulations: a future nanomedicine for cancer

MM Yallapu, M Jaggi, SC Chauhan - Drug discovery today, 2012 - Elsevier
Curcumin, a natural diphenolic compound derived from turmeric Curcuma longa, has proven
to be a modulator of intracellular signaling pathways that control cancer cell growth …