Importance In the US, tuberculosis remains an important preventable disease, including
active tuberculosis, which may be infectious, and latent tuberculosis infection (LTBI), which …

The current active–latent paradigm of tuberculosis largely neglects the documented
spectrum of disease. Inconsistency with regard to definitions, terminology, and diagnostic …

Background Tuberculosis (TB) is the leading infectious cause of death globally. Several
preventive measures are employed to prevent TB, yet there is a paucity of evidence on the …

The US Preventive Services Task Force (USPSTF) has recommended screening of adults at
increased risk for latent tuberculosis (TB) infection (LTBI). 1 This recommendation (B …

Importance Elimination of tuberculosis (TB) disease in the US hinges on the ability of tests to
detect individual risk of developing disease to inform prevention. The relative performance of …

Objectives The interferon-gamma releasing assay (IGRA) has been widely used to diagnose
latent tuberculosis infection (TBI). However, there are limited data on the association …

In countries with low tuberculosis (TB) incidence, the systematic testing and treatment of
latent TB infection (LTBI) in contacts of pulmonary TB index cases is the standard of care …

Methods We conducted a single-center retrospective case-control study, including 130
outpatients with LTBI treated with INH between July 2019 and March 2022. Participants who …

This document is the result of the deliberations of the Committee on Emerging Pathogens
and COVID-19 of the Illustrious Official College of Physicians of Madrid (ICOMEM) regarding …

This review presents a comprehensive examination of the contemporary landscape
pertaining to latent tuberculosis infection (LTBI) diagnostics, with a particular emphasis on …