Introduction: Antipsychotic polypharmacy (APP), the concomitant use of≥ 2 antipsychotics,
is common in clinical practice. Prior reviews have focused on the efficacy of APP, but no …

In this article we examine the two major classes of side effects with atypical antipsychotics:
extrapyramidal symptoms (EPS) and the metabolic syndrome (the triad of diabetes …

Background: Weight gain is a side effect of therapy with many atypical antipsychotics and
may have important clinical repercussions with respect to long-term health and treatment …

Objective: Osteoporosis occurs in common psychiatric conditions and causes significant
morbidity. Many neuroleptic medications can cause hyperprolactinemia, which can then …

Introduction Psychotropic medication use is associated with weight gain. While there are
studies and reviews comparing weight gain for psychotropics within some classes, clinicians …

A systematic and comprehensive literature search was performed to determine the extent of
weight gain induced by risperidone (RIS) treatment across the age span. The review and …

Objective: To evaluate the efficacy and safety of quetiapine monotherapy for mania in
bipolar disorder by an a priori defined combined analysis of data from two placebo …

Research on the concept of craving may lead to better understanding of the biobehavioural
circuitries that contribute to the complexity of alcohol use disorders (AUDs). The experiences …

Classic and modern antipsychotics can induce substantial weight gain causing diabetes,
lipid abnormalities and psychological distress. Treatment emergent weight gain varies within …

Background: This naturalistic cross-sectional survey of patients with severe mental illnesses
explores the association between important variables and obesity, extreme obesity, diabetes …