[HTML][HTML] Anti-inflammatory effects of dietary polyphenols through inhibitory activity against metalloproteinases

T Suzuki, T Ohishi, H Tanabe, N Miyoshi, Y Nakamura - Molecules, 2023 - mdpi.com
Matrix metalloproteinases (MMPs) are zinc-dependent metalloproteinases that play
important roles in a variety of diseases, including cancer, cardiovascular disease, diabetes …

Absorption, metabolism, bioactivity, and biotransformation of epigallocatechin gallate

S Zhang, B Mao, S Cui, Q Zhang, J Zhao… - Critical Reviews in …, 2024 - Taylor & Francis
Epigallocatechin gallate (EGCG), a typical flavone-3-ol polyphenol containing eight free
hydroxyl groups, is associated with a variety of bioactivities, such as antioxidant, anti …

[HTML][HTML] Antidiabetic drugs in the treatment of Alzheimer's disease

M Michailidis, DA Tata, D Moraitou… - International journal of …, 2022 - mdpi.com
The public health burden of type 2 diabetes mellitus and Alzheimer's disease is steadily
increasing worldwide, especially in the population of older adults. Epidemiological and …

[HTML][HTML] Anti-diabetic prospects of dietary bio-actives of millets and the significance of the gut microbiota: A case of finger millet

V Singh, GD Lee, HW Son, S Amani… - Frontiers in …, 2022 - frontiersin.org
Finger millet (Eleusine coracana) is a staple food in several parts of the world because of its
high nutritional value. In addition to its high nutrient content, finger millet contains numerous …

[HTML][HTML] Nurturing through nutrition: exploring the role of antioxidants in maternal diet during pregnancy to mitigate developmental programming of chronic diseases

MS Diniz, CC Magalhães, C Tocantins, LF Grilo… - Nutrients, 2023 - mdpi.com
Chronic diseases represent one of the major causes of death worldwide. It has been
suggested that pregnancy-related conditions, such as gestational diabetes mellitus (GDM) …

Interaction of high amylose corn starch with polyphenols: Modulating the stability of polyphenols with different structure against thermal processing

H Fan, X Yao, Z Chen, R Ma, Y Wen, H Li, J Wang… - Food Chemistry, 2024 - Elsevier
Polyphenols are known to undergo thermal degradation and their bioactivity is reduced. In
this study, the thermal degradation of polyphenols was modulated by the complexation …

[HTML][HTML] Natural inhibitors of mammalian α-Amylases as promising drugs for the treatment of metabolic diseases

AP Kalinovskii, OV Sintsova, IN Gladkikh… - International journal of …, 2023 - mdpi.com
α-Amylase is a generally acknowledged molecular target of a distinct class of antidiabetic
drugs named α-glucosidase inhibitors. This class of medications is scarce and rather …

Research progress on drugs for diabetes based on insulin receptor/insulin receptor substrate

J Su, L Tang, Y Luo, J Xu, S Ouyang - Biochemical Pharmacology, 2023 - Elsevier
The number of people with diabetes worldwide is increasing annually, resulting in a serious
economic burden. Insulin resistance is a major pathology in the early onset of diabetes …

[HTML][HTML] The anti-diabetic potential of baicalin: evidence from rodent studies

T Szkudelski, K Szkudelska - International Journal of Molecular Sciences, 2023 - mdpi.com
Baicalin is a biologically active flavonoid compound that benefits the organism in various
pathological conditions. Rodent studies have shown that this compound effectively …

Quercetin ameliorated cardiac injury via reducing inflammatory actions and the glycerophospholipid metabolism dysregulation in a diabetic cardiomyopathy mouse …

C Jiang, D Li, L Chen, Y Liu, Y Zhao, G Mei, Y Tang… - Food & Function, 2022 - pubs.rsc.org
Quercetin has multiple protective effects against cardiometabolic diseases, but the biological
mechanisms underlying the benefits in diabetic cardiomyopathy (DCM) are unclear. A …