Over the past few decades, substantial evidence has convincingly revealed the existence of
cancer stem cells (CSCs) as a minor subpopulation in cancers, contributing to an aberrantly …

As a phenolic acid compound, caffeic acid (CA) can be isolated from different sources such
as tea, wine and coffee. Caffeic acid phenethyl ester (CAPE) is naturally occurring derivative …

Ferroptosis is a newly defined form of regulated cell death (RCD) characterized by iron
overload, lipid reactive oxygen species (ROS) accumulation, and lipid peroxidation, which is …

Flavonoids represent an important group of bioactive compounds derived from plant-based
foods and beverages with known biological activity in cells. From the modulation of …

Autophagy is a delicate intracellular degradation process that occurs due to diverse stressful
conditions, including the accumulation of damaged proteins and organelles as well as …

The lysosomes of cancer cells have lower pH and higher viscosity than those of normal
cells. These features can be used as sensitive and selective markers for cancer diagnosis. In …

The inception of cancer treatment with chemotherapeutics began in the 1940s with nitrogen
mustards that were initially employed as weapons in World War II. Since then, treatment …

Autophagy is an evolutionarily conserved process for the degradation of redundant or
damaged cellular material by means of a lysosome-dependent mechanism, contributing to …

Abstract Timosaponin AIII (Tim-AIII), a steroid saponin, exhibits strong anticancer activity in a
variety of cancers, especially breast cancer and liver cancer. However, the underlying …

Simple Summary The metabolism of carbohydrates and lipids is essential to meet the
diverse needs of cells. The autophagy cellular pathway is crucial for normal cellular function …