[HTML][HTML] Global prevalence and effect of comorbidities and smoking status on severity and mortality of COVID-19 in association with age and gender: a systematic …

S Chenchula, K Vidyasagar, S Pathan, S Sharma… - Scientific reports, 2023 - nature.com
A COVID-19 patient often presents with multiple comorbidities and is associated with
adverse outcomes. A comprehensive assessment of the prevalence of comorbidities in …

[HTML][HTML] Respiratory system mechanics, gas exchange, and outcomes in mechanically ventilated patients with COVID-19-related acute respiratory distress syndrome …

MP Reddy, A Subramaniam, C Chua… - The Lancet …, 2022 - thelancet.com
The association of respiratory mechanics, particularly respiratory system static compliance
(C RS), with severity of hypoxaemia in patients with COVID-19-related acute respiratory …

[HTML][HTML] Effects of adding L-arginine orally to standard therapy in patients with COVID-19: A randomized, double-blind, placebo-controlled, parallel-group trial. Results …

G Fiorentino, A Coppola, R Izzo, A Annunziata… - …, 2021 - thelancet.com
Background We and others have previously demonstrated that the endothelium is a primary
target of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and L …

[HTML][HTML] Extended prone positioning for intubated ARDS: a review

T Walter, JD Ricard - Critical Care, 2023 - Springer
During the COVID-19 pandemic, several centers had independently reported extending
prone positioning beyond 24 h. Most of these centers reported maintaining patients in prone …

[HTML][HTML] Prevalent diabetes and long-term cardiovascular outcomes in adult sepsis survivors: a population-based cohort study

F Angriman, PR Lawler, BR Shah, CM Martin… - Critical Care, 2023 - Springer
Background Sepsis survivors are at elevated risk for cardiovascular disease during long-
term follow-up. Whether diabetes influences cardiovascular risk after sepsis survival remains …

[HTML][HTML] Respiratory support in patients with severe COVID-19 in the International Severe Acute Respiratory and Emerging Infection (ISARIC) COVID-19 study: a …

LF Reyes, S Murthy, E Garcia-Gallo, L Merson… - Critical care, 2022 - Springer
Background Up to 30% of hospitalised patients with COVID-19 require advanced respiratory
support, including high-flow nasal cannulas (HFNC), non-invasive mechanical ventilation …

Clinical characteristics, respiratory management, and determinants of oxygenation in COVID-19 ARDS: A prospective cohort study

E Estenssoro, CI Loudet, A Dubin, VSK Edul… - Journal of critical …, 2022 - Elsevier
Purpose To identify determinants of oxygenation over time in patients with COVID-19 acute
respiratory distress syndrome (ARDS); and to analyze their characteristics according to …

[HTML][HTML] Intensive care and organ support related mortality in patients with COVID-19: A systematic review and meta-analysis

A Chandel, S Leazer, KC Alcover, J Farley… - Critical Care …, 2023 - journals.lww.com
OBJECTIVES: To perform a systematic review and meta-analysis to generate estimates of
mortality in patients with COVID-19 that required hospitalization, ICU admission, and organ …

Effect of high altitude on the survival of COVID-19 patients in Intensive Care Unit: a cohort study

M Jibaja, E Roldan-Vasquez, J Rello… - Journal of Intensive …, 2022 - journals.sagepub.com
Purpose: The effect of high altitude (≥ 1500 m) and its potential association with mortality by
COVID-19 remains controversial. We assessed the effect of high altitude on the …

Differences in clinical characteristics and outcomes between COVID-19 and influenza in critically ill adult patients: a national database study

D Naouri, T Pham, M Dres, A Vuagnat, G Beduneau… - Journal of Infection, 2023 - Elsevier
Objective Prior to the coronavirus disease 2019 (COVID-19) pandemic, influenza was the
most frequent cause of viral respiratory pneumonia requiring intensive care unit (ICU) …