Monoclonal antibodies for the treatment of cancer
CW Shuptrine, R Surana, LM Weiner - Seminars in cancer biology, 2012 - Elsevier
Over the past decade, the clinical utility of monoclonal antibodies has been realized and
antibodies are now a mainstay for the treatment of cancer. Antibodies have the unique …
antibodies are now a mainstay for the treatment of cancer. Antibodies have the unique …
Management of cutaneous squamous cell carcinoma in patients with epidermolysis bullosa: best clinical practice guidelines
JE Mellerio, SJ Robertson, C Bernardis… - British Journal of …, 2016 - academic.oup.com
This article summarizes recommendations reached following a systematic literature review
and expert consensus on the diagnosis and management of cutaneous squamous cell …
and expert consensus on the diagnosis and management of cutaneous squamous cell …
Biological determinants of radioresistance and their remediation in pancreatic cancer
P Seshacharyulu, MJ Baine, JJ Souchek… - … et Biophysica Acta (BBA …, 2017 - Elsevier
Despite recent advances in radiotherapy, a majority of patients diagnosed with pancreatic
cancer (PC) do not achieve objective responses due to the existence of intrinsic and …
cancer (PC) do not achieve objective responses due to the existence of intrinsic and …
[HTML][HTML] Nimotuzumab: beyond the EGFR signaling cascade inhibition
One of the most known oncogenes is the epidermal growth factor receptor (EGFR) family. It
activates multiple signaling cascades that promote carcinogenesis and immune evasion …
activates multiple signaling cascades that promote carcinogenesis and immune evasion …
Approval summary: cetuximab in combination with cisplatin or carboplatin and 5‐fluorouracil for the first‐line treatment of patients with recurrent locoregional or …
MH Cohen, H Chen, S Shord, C Fuchs, K He… - The …, 2013 - academic.oup.com
Abstract Learning Objectives Compare survival outcomes among patients with SCCHN
treated with a platinum/5‐FU regimen with and without cetuximab. Compare adverse event …
treated with a platinum/5‐FU regimen with and without cetuximab. Compare adverse event …
mTHPC mediated photodynamic therapy (PDT) of squamous cell carcinoma in the head and neck: a systematic review
SAHJ de Visscher, PU Dijkstra, IB Tan… - Oral oncology, 2013 - Elsevier
OBJECTIVE: Photodynamic therapy (PDT) is used in curative and palliative treatment of
head and neck squamous cell carcinoma (HNSCC). To evaluate available evidence on the …
head and neck squamous cell carcinoma (HNSCC). To evaluate available evidence on the …
[HTML][HTML] Inhibition of radiation induced migration of human head and neck squamous cell carcinoma cells by blocking of EGF receptor pathways
AC Pickhard, J Margraf, A Knopf, T Stark, G Piontek… - BMC cancer, 2011 - Springer
Background Recently it has been shown that radiation induces migration of glioma cells and
facilitates a further spread of tumor cells locally and systemically. The aim of this study was …
facilitates a further spread of tumor cells locally and systemically. The aim of this study was …
[HTML][HTML] Immune biomarkers of anti-EGFR monoclonal antibody therapy
The tumor antigen (TA)-targeted monoclonal antibodies (mAb) cetuximab and panitumumab
target the human epidermal growth factor receptor and have been integrated into treatment …
target the human epidermal growth factor receptor and have been integrated into treatment …
Toxicities of systemic agents in squamous cell carcinoma of the head and neck (SCCHN); A new perspective in the era of immunotherapy
NF Saba, MD Mody, ES Tan, HS Gill, A Rinaldo… - Critical Reviews in …, 2017 - Elsevier
Squamous cell carcinoma of the head and neck (SCCHN) is a difficult to treat malignancy
and represents the seventh most common cancer worldwide. Systemic therapy has a critical …
and represents the seventh most common cancer worldwide. Systemic therapy has a critical …
[HTML][HTML] Advances in molecular targeted therapies to increase efficacy of (chemo) radiation therapy
K Viktorsson, T Rieckmann, M Fleischmann… - Strahlentherapie und …, 2023 - Springer
Recent advances in understanding the tumor's biology in line with a constantly growing
number of innovative technologies have prompted characterization of patients' individual …
number of innovative technologies have prompted characterization of patients' individual …