[HTML][HTML] A novel ligand-receptor relationship between families of ribonucleases and receptor tyrosine kinases
Pancreatic ribonuclease is known to participate in host defense system against pathogens,
such as parasites, bacteria, and virus, which results in innate immune response …
such as parasites, bacteria, and virus, which results in innate immune response …
Antiproliferative and proapoptotic activity of CLM3, a novel multiple tyrosine kinase inhibitor, alone and in combination with SN-38 on endothelial and cancer cells
Aims To demonstrate the antiproliferative and pro-apoptotic activity of the novel
pyrazolopyrimidine derivative multiple tyrosine kinase inhibitor CLM3, alone and in …
pyrazolopyrimidine derivative multiple tyrosine kinase inhibitor CLM3, alone and in …
Molecular genetics of head and neck cancer
S Arora, P Aggarwal, A Pathak… - Molecular …, 2012 - spandidos-publications.com
Understanding of molecular regulatory pathways presents a novel therapeutic approach for
the treatment of head and neck cancer. These specific check points are becoming the …
the treatment of head and neck cancer. These specific check points are becoming the …
EGFR pathway-based gene signatures of druggable gene mutations in melanoma, breast, lung, and thyroid cancers
M Raevskiy, M Sorokin, U Vladimirova… - Biochemistry …, 2021 - Springer
Abstract EGFR, BRAF, PIK3CA, and KRAS genes play major roles in EGFR pathway, and
accommodate activating mutations that predict response to many targeted therapeutics …
accommodate activating mutations that predict response to many targeted therapeutics …
Cemiplimab for locally advanced cutaneous squamous cell carcinoma: safety, efficacy, and position in therapy panel
E Lebas, N Marchal, A Rorive… - Expert Review of …, 2021 - Taylor & Francis
Introduction Locally advanced cutaneous squamous cell carcinoma (lacSCC) is rare.
Approximately one-fourth of the cases are observed among immunocompromised patients …
Approximately one-fourth of the cases are observed among immunocompromised patients …
[HTML][HTML] Prospective, observational practice survey of applied skin care and management of cetuximab-related skin reactions: PROSKIN study
SI Rothschild, D Betticher, R Zenhäusern… - Cancer chemotherapy …, 2019 - Springer
Purpose The study aimed to investigate strategies to prevent and treat cetuximab-induced
skin reactions and their perceived effectiveness in patients with metastatic colorectal cancer …
skin reactions and their perceived effectiveness in patients with metastatic colorectal cancer …
[HTML][HTML] Effectiveness of cetuximab in combination with concurrent chemoradiotherapy in locoregionally advanced nasopharyngeal carcinoma: a 1: 2 propensity score …
LR Wu, H Zhu, J Xu, X Jiang, L Yin, N Jiang… - Journal of …, 2018 - ncbi.nlm.nih.gov
Background: This study aimed to compare concurrent chemoradiotherapy (CCRT) plus
cetuximab (C) with CCRT alone in locoregionally advanced nasopharyngeal carcinoma …
cetuximab (C) with CCRT alone in locoregionally advanced nasopharyngeal carcinoma …
[HTML][HTML] Synthesis and evaluation of 2-amine-4-oxyphosaniline pyrimidine derivatives as EGFR L858R/T790M/C797S mutant inhibitors
M Zhang, Y Yang, Y Wang, J Wang, H Wu… - Chemical and …, 2023 - jstage.jst.go.jp
Epidermal growth factor receptor (EGFR) C797S mutation leads to Osimertinib drug
resistance by disturbing the covalent biding of Michael acceptor group to the Cys797 …
resistance by disturbing the covalent biding of Michael acceptor group to the Cys797 …
Efficacy and toxicity of weekly paclitaxel, carboplatin, and cetuximab as induction chemotherapy or in cases of metastases or relapse for head and neck cancer with a …
R Forman, H Deshpande, B Burtness… - Head & Neck, 2022 - Wiley Online Library
Background Paclitaxel, carboplatin, and cetuximab (PCC) has shown promise as induction
chemotherapy and in patients with metastatic/recurrent head and neck cancer (HNC). Given …
chemotherapy and in patients with metastatic/recurrent head and neck cancer (HNC). Given …
Head, neck, and oral cancer update
C Farris, DME Petitte - Home Healthcare Now, 2013 - journals.lww.com
Although the overall incidence of head, neck, and oral cancer has been decreasing, oral
and neck cancer caused by the human papillomavirus (HPV) has risen. This article …
and neck cancer caused by the human papillomavirus (HPV) has risen. This article …