[HTML][HTML] Physical exercise in the prevention and treatment of Alzheimer's disease

A De la Rosa, G Olaso-Gonzalez… - Journal of sport and …, 2020 - Elsevier
Dementia is one of the greatest global challenges for health and social care in the 21st
century. Alzheimer's disease (AD), the most common type of dementia, is by no means an …

Importance of assessing cardiorespiratory fitness in clinical practice: a case for fitness as a clinical vital sign: a scientific statement from the American Heart Association

R Ross, SN Blair, R Arena, TS Church, JP Després… - Circulation, 2016 - Am Heart Assoc
Mounting evidence has firmly established that low levels of cardiorespiratory fitness (CRF)
are associated with a high risk of cardiovascular disease, all-cause mortality, and mortality …

Cerebral perfusion and the risk of dementia: a population-based study

FJ Wolters, HI Zonneveld, A Hofman, A Van Der Lugt… - Circulation, 2017 - Am Heart Assoc
Background: Cerebral hypoperfusion has previously been associated with mild cognitive
impairment and dementia in various cross-sectional studies, but whether hypoperfusion …

Hierarchical feature representation and multimodal fusion with deep learning for AD/MCI diagnosis

HI Suk, SW Lee, D Shen… - NeuroImage, 2014 - Elsevier
For the last decade, it has been shown that neuroimaging can be a potential tool for the
diagnosis of Alzheimer's Disease (AD) and its prodromal stage, Mild Cognitive Impairment …

Alzheimer disease: epidemiology, diagnostic criteria, risk factors and biomarkers

C Reitz, R Mayeux - Biochemical pharmacology, 2014 - Elsevier
The global prevalence of dementia is as high as 24 million, and has been predicted to
quadruple by the year 2050. In the US alone, Alzheimer disease (AD)–the most frequent …

Cerebral hypoperfusion and glucose hypometabolism: Key pathophysiological modulators promote neurodegeneration, cognitive impairment, and Alzheimer's …

MA Daulatzai - Journal of neuroscience research, 2017 - Wiley Online Library
Aging, hypertension, diabetes, hypoxia/obstructive sleep apnea (OSA), obesity, vitamin
B12/folate deficiency, depression, and traumatic brain injury synergistically promote diverse …

Positron emission tomography and magnetic resonance imaging methods and datasets within the Dominantly Inherited Alzheimer Network (DIAN)

NS McKay, BA Gordon, RC Hornbeck, A Dincer… - Nature …, 2023 - nature.com
Abstract The Dominantly Inherited Alzheimer Network (DIAN) is an international
collaboration studying autosomal dominant Alzheimer disease (ADAD). ADAD arises from …

Glial and neuronal control of brain blood flow

D Attwell, AM Buchan, S Charpak, M Lauritzen… - Nature, 2010 - nature.com
Blood flow in the brain is regulated by neurons and astrocytes. Knowledge of how these
cells control blood flow is crucial for understanding how neural computation is powered, for …

Vascular dysfunction in Alzheimer's disease: a prelude to the pathological process or a consequence of it?

K Govindpani, LG McNamara, NR Smith… - Journal of clinical …, 2019 - mdpi.com
Alzheimer's disease (AD) is the most prevalent form of dementia. Despite decades of
research following several theoretical and clinical lines, all existing treatments for the …

The clinical use of structural MRI in Alzheimer disease

GB Frisoni, NC Fox, CR Jack Jr, P Scheltens… - Nature Reviews …, 2010 - nature.com
Structural imaging based on magnetic resonance is an integral part of the clinical
assessment of patients with suspected Alzheimer dementia. Prospective data on the natural …