Nine traditional Chinese herbal formulas for the treatment of depression: an ethnopharmacology, phytochemistry, and pharmacology review

D Feng, T Tang, X Lin, Z Yang, S Yang… - Neuropsychiatric …, 2016 - Taylor & Francis
Depression is a major mental disorder, and is currently recognized as the second-leading
cause of disability worldwide. However, the therapeutic effect of antidepressants remains …

Antidepressant-Like Effects of Chaihu Shugan Powder (柴胡疏肝散) on Rats Exposed to Chronic Unpredictable Mild Stress through Inhibition of Endoplasmic …

K Sun, Y Jin, Z Mei, Z Feng, J Liu, M Cao… - Chinese journal of …, 2021 - Springer
Objective To investigate the antidepressant-like effects of Chaihu Shugan Powder (CSP,
柴胡疏肝散) and to explore its underlying mechanisms. Methods Thirty-two Sprague-Dawley …

Antidepressant‐Like Effects and Cognitive Enhancement of Coadministration of Chaihu Shugan San and Fluoxetine: Dependent on the BDNF‐ERK‐CREB Signaling …

L Yan, X Xu, Z He, S Wang, L Zhao… - BioMed research …, 2020 - Wiley Online Library
Background. Fluoxetine (FLU) is the first‐line and widely used medication for depression;
however, FLU treatment is almost ineffective in 30%‐40% of patients with depression. In …

Impact of traditional Chinese medicine treatment on chronic unpredictable mild stress-induced depression-like behaviors: intestinal microbiota and gut microbiome …

W Qu, S Liu, W Zhang, H Zhu, Q Tao, H Wang, H Yan - Food & function, 2019 - pubs.rsc.org
Gut microbiota dysbiosis is a recognized contributing factor to many noncommunicable
diseases, but more evidence is still needed to illustrate its causative impact on mental and …

Managing Depression with Bupleurum chinense Herbal Formula: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

L Yang, JL Shergis, YM Di, AL Zhang, C Lu… - The Journal of …, 2020 - liebertpub.com
Objectives: Bupleurum chinense (BC; Radix Bupleuri) formulae are widely used in herbal
medicine clinical practice for major depressive disorder (MDD). This study provides an up-to …

[PDF][PDF] Effect of fluoxetine and resveratrol on testicular functions and oxidative stress in a rat model of chronic mild stress-induced depression

HF Sakr, AM Abbas, AZ Elsamanoudy… - J Physiol …, 2015 - academia.edu
Our objective was to investigate the effects of chronic unpredictable mild stress (CUMS) with
or without selective serotonin reuptake inhibitor (fluoxetine) and anti-oxidant (resveratrol) on …

Network pharmacology and experimental evidence: PI3K/AKT signaling pathway is involved in the antidepressive roles of Chaihu Shugan San

S Zhang, Y Lu, W Chen, W Shi, Q Zhao… - Drug Design …, 2021 - Taylor & Francis
Objective Chaihu Shugan San (CSS) is a common antidepressant prescription in traditional
Chinese medicines. However, its active ingredients and mechanisms are unknown. The aim …

[HTML][HTML] Database-aided UHPLC-Q-orbitrap MS/MS strategy putatively identifies 52 compounds from Wushicha Granule to propose anti-counterfeiting quality …

X Li, S Chen, J Zeng, R Cai, Y Liang, C Chen, B Chen… - Chinese Medicine, 2023 - Springer
Wushicha Granule, an over-the-counter-drug (OTC) prescription, consists of 19 traditional
Chinese herbals medicines (CHMs), such as Chaihu, Hongcha, Chuanxiong, Houpo, and …

The Antidepressant Effect of Angelica sinensis Extracts on Chronic Unpredictable Mild Stress‐Induced Depression Is Mediated via the Upregulation of the BDNF …

J Shen, J Zhang, M Deng, Y Liu, Y Hu… - Evidence‐Based …, 2016 - Wiley Online Library
Angelica sinensis (AS), a traditional Chinese herbal medicine, has pharmaceutical effects
on menstrual illness, cerebrovascular diseases, cardiovascular diseases, and cognitive …

[HTML][HTML] Proteomics study reveals the anti-depressive mechanisms and the compatibility advantage of chaihu-shugan-san in a rat model of chronic unpredictable mild …

X Zhu, T Li, E Hu, L Duan, C Zhang, Y Wang… - Frontiers in …, 2022 - frontiersin.org
Background: Chaihu-Shugan-San is a classical prescription to treat depression. According
to the traditional Chinese medicine (TCM) principle, the 2 decomposed recipes in Chaihu …