Management of patients with prostate cancer (PCa) is often challenging due to the
difference in the biology of cancer between patients and the various genetic alterations …

Tumor-adjacent normal (TAN) tissues, which constitute tumor microenvironment and are
different from healthy tissues, provide critical information at molecular levels that can be …

Abstract Background Prostate cancer (PCa) is one of the most prevalent cancers worldwide.
The clinical manifestations and molecular characteristics of PCa are highly variable …

Novel biomarkers are urgently needed to improve the prediction of clinical outcomes and
guide personalized treatment for prostate cancer (PCa) patients. However, the role of N6 …

Prostate cancer (PCa) is a heterogeneous disease with highly variable clinical outcomes
which presents enormous challenges in the clinical management. A vast amount of …

Prostate cancer (PCa) is a prevalent malignancy among men worldwide, and biochemical
recurrence (BCR) after radical prostatectomy (RP) is a critical turning point commonly used …

Background Clinical manifestation of prostate cancer (PCa) is highly variable. Aggressive
tumors require radical treatment while clinically non-significant ones may be suitable for …

Nonmutational epigenetic reprogramming is a crucial mechanism contributing to the
pronounced heterogeneity of prostate cancer (PCa). Among these mechanisms, N6 …

Limited information is available on potential predictive value of environmental chemicals for
mortality. Our study aimed to investigate the associations between 43 of 8 classes …

In flowering plants, C4 photosynthesis is superior to C3 type in carbon fixation efficiency and
adaptation to extreme environmental conditions, but the mechanisms behind the assembly …