Inflammation is a complex and necessary component of the response to biological,
chemical, or physical stimuli, and the cellular and molecular events that initiate and regulate …

It is well-known that deficiency or over exposure to various elements has noticeable effects
on human health. The effect of an element is determined by several characteristics …

Anaemia is a commonly diagnosed complication among patients suffering with chronic
kidney disease. If left untreated, it may affect patient quality of life. There are several causes …

Small-molecule stabilizers of hypoxia inducible factor (HIF) are being developed for the
treatment of renal anaemia. These molecules inhibit prolyl hydroxylase domain-containing …

The increasing prevalence of older-age people in our society represents the culmination of
centuries of medical, scientific, and social endeavors. At least in Western society, now …

As there is strong evidence for inflammation and oxidative stress in depression, the aim of
this study was to elucidate the relationship between oxidative imbalance and cellular …

Background: There is limited insight into the attributable effect of anemia and comorbidity on
functional status and mortality in old age. Methods: The Leiden 85-plus Study is a population …

Blood viscosity is increased by elevated concentrations of acute phase reactants and
hypergammaglobulinemia in inflammation. These increase blood viscosity by increasing …

Aging is a multifactorial process that depends on diverse molecular and cellular
mechanisms, such as genome maintenance and inflammation. The nuclear enzyme poly …

Background: Anemia is inevitable as chronic kidney disease (CKD) advances. With the
advent of erythropoietin-stimulating agents (ESAs), considerable improvement has been …