Diagnosis and management of primary central nervous system lymphoma

CH Han, TT Batchelor - Cancer, 2017 - Wiley Online Library
Primary central nervous system lymphoma (PCNSL) is a rare and aggressive extranodal
non‐Hodgkin lymphoma (NHL) that is confined to the brain, eyes, spinal cord, or …

Misleading reporting (spin) in noninferiority randomized clinical trials in oncology with statistically not significant results: a systematic review

C Ito, A Hashimoto, K Uemura, K Oba - JAMA network open, 2021 - jamanetwork.com
Importance Spin, the inaccurate reporting of randomized clinical trials (RCTs) with results
that are not statistically significant for the primary end point, distorts interpretation of results …

Guidelines for the diagnosis and management of primary central nervous system diffuse large B‐cell lymphoma.

CP Fox, EH Phillips, J Smith, K Linton… - British journal of …, 2019 - search.ebscohost.com
The article offers guidelines for the diagnosis and management of primary central nervous
system diffuse large B-cell lymphoma. It informs on symptoms associated with the disease …

High‐throughput proteomic analysis of FFPE tissue samples facilitates tumor stratification

Y Zhu, T Weiss, Q Zhang, R Sun, B Wang… - Molecular …, 2019 - Wiley Online Library
Formalin‐fixed, paraffin‐embedded (FFPE), biobanked tissue samples offer an invaluable
resource for clinical and biomarker research. Here, we developed a pressure cycling …

Therapy of primary CNS lymphoma: role of intensity, radiation, and novel agents

AJM Ferreri - Hematology 2014, the American Society of …, 2017 - ashpublications.org
Primary central nervous system (CNS) lymphomas represent a subgroup of malignancies
with specific characteristics, an aggressive course, and unsatisfactory outcome in contrast …

Primary CNS lymphoma in the elderly: the challenge

T Siegal, O Bairey - Acta Haematologica, 2019 - karger.com
Primary central nervous system (CNS) lymphoma is an aggressive brain tumor sensitive to
chemotherapy and radiotherapy. Its incidence has increased in the elderly, and they account …

Early whole brain radiotherapy in primary CNS lymphoma: negative impact on quality of life in the randomized G-PCNSL-SG1 trial

U Herrlinger, N Schäfer, R Fimmers… - Journal of cancer …, 2017 - Springer
Purpose In the randomized G-PCNSL-SG-1 trial, the addition of whole brain radiotherapy
(45 Gy) to high-dose methotrexate (HD-MTX)-based chemotherapy (early WBRT arm) did …

A systematic review of high-dose methotrexate for adults with primary central nervous system lymphoma

G Villanueva, M Guscott, P Schaiquevich, C Sampor… - Cancers, 2023 - mdpi.com
Simple Summary High-dose methotrexate (HDMTX) is the backbone of induction therapy for
primary central nervous system lymphoma (PCNSL). There are numerous different protocols …

Targeted therapies and immune checkpoint inhibitors in primary CNS lymphoma

HG Wirsching, M Weller, S Balabanov, P Roth - Cancers, 2021 - mdpi.com
Simple Summary Primary central nervous system lymphoma is a rare disease with limited
therapeutic options. A more profound understanding of the molecular mechanisms that …

Primary central nervous system lymphomas

U Chukwueke, C Grommes… - Hematology/Oncology …, 2022 - hemonc.theclinics.com
Primary central nervous system lymphoma (PCNSL) is an aggressive variant of extranodal
non-Hodgkin lymphoma (NHL) arising within the brain, leptomeninges, eyes, or spinal cord …