Urinary tract infections (UTIs) are among the most common bacterial infections seen in
clinical practice. The ascent of UTI-causing pathogens to the kidneys results in …

Pore-forming toxins (PFTs) are widely distributed in both Gram-negative and Gram-positive
bacteria. PFTs can act as virulence factors that bacteria utilise in dissemination and host …

The NLRP3 inflammasome is a key regulator of inflammation that responds to a broad range
of stimuli. The exact mechanism of activation has not been determined, but there is a …

Gram-positive bacterial infection causes high morbidity and mortality worldwide, while the
underlying mechanism for host sensing bacterial components and initiating immune …

Background Urinary tract infections (UTIs) are one the most common infections. The rapid
and accurate identification of uropathogens, and the determination of antimicrobial …

Kidney transplantation is the best available renal replacement therapy for patients with end-
stage kidney disease and is associated with better quality of life and patient survival …

The abnormal activation of the NLRP3 inflammasome is closely related to the occurrence
and development of many inflammatory diseases. Targeting the NLRP3 inflammasome has …

The Gram-negative bacterium Kingella kingae is part of the commensal oropharyngeal flora
of young children. As detection methods have improved, K. kingae has been increasingly …

Urinary tract infection (UTI), a prevalent disease in India, also ranks among the most
common infections in developing countries. The rapid emergence of antibiotic-resistant …

Neutrophils play a crucial role in immune defense against and clearance of uropathogenic
Escherichia coli (UPEC)‐mediated urinary tract infection, the most common bacterial …