Recent progress of supramolecular chemotherapy based on host–guest interactions

M Yan, S Wu, Y Wang, M Liang, M Wang… - Advanced …, 2024 - Wiley Online Library
Chemotherapy is widely recognized as an effective approach for treating cancer due to its
ability to eliminate cancer cells using chemotherapeutic drugs. However, traditional …

Molecular recognition with macrocyclic receptors for application in precision medicine

YC Pan, JH Tian, DS Guo - Accounts of Chemical Research, 2023 - ACS Publications
Conspectus Macrocyclic receptors can serve as alternatives to natural recognition systems
as recognition tools. They provide effectively preorganized cavities to encapsulate guests …

Rational design of T-cell-and B-cell-based therapeutic cancer vaccines

WH Li, JY Su, YM Li - Accounts of Chemical Research, 2022 - ACS Publications
Conspectus Cancer vaccines provide an efficient strategy to enhance tumor-specific
immune responses by redeploying immune systems. Despite the approval of the first cancer …

Molecular recognition of cyclophanes in water

FY Chen, WC Geng, K Cai, DS Guo - Chinese Chemical Letters, 2023 - Elsevier
Molecular recognition in water, the biological solvent, always receives significant research
focus in supramolecular chemistry. The mechanisms of molecular recognition in water is key …

[HTML][HTML] Guest adaptative supramolecular sensing strategy for warning the risky aflatoxins in contaminated cereals

D Wang, W Li, W Cheng, Y Wang, Z Zheng… - Journal of Hazardous …, 2024 - Elsevier
In the face of diversified analytes, it is a great challenge and infeasible task to design and
synthesize corresponding macrocyclic hosts to realize the ideal supramolecular sensing …

Heterocyclic Molecules Tethered Branched Polymers with Innate Immune Stimulating Activity

J Zhao, L Liu, Y Wang, Z Huang, Y Zhang… - Ccs …, 2024 - chinesechemsoc.org
We report herein an interesting finding that heterocyclic molecules tethered branched
polymers exhibit innate immune stimulating activity. When we conjugated a series of five …

Expanding the hydrophobic cavity surface of azocalix [4] arene to enable biotin/avidin affinity with controlled release

FY Chen, CZ Li, H Han, WC Geng… - Angewandte …, 2024 - Wiley Online Library
The development of artificial receptors that combine ultrahigh‐affinity binding and
controllable release for active guests holds significant importance in biomedical …

Renal-clearable luminescent gold nanoparticles incorporating active and bio-orthogonal tumor-targeting for drug delivery and controlled release

K He, C Hu, YF Ding, W Cai, D Huang, L Mo, J Liu… - Nano Today, 2024 - Elsevier
The use of ultrasmall gold nanoparticles (AuNPs) as drug delivery systems (DDSs)
represents certain challenges, including limited targeting efficiency, uncontrolled drug …

Azocalixarenes: A scaffold of universal excipients with high efficiency

YX Yue, YL Lin, MM Chen, HW Tian, R Ma… - Science China …, 2024 - Springer
Excipients are important components of pharmaceutical preparations that affect their quality,
safety, and efficacy. Macrocyclic receptors are a family of supramolecular excipients with …

Supramolecular systems for bioapplications: recent research progress in China

YY Liu, XY Yu, YC Pan, H Yin, S Chao, Y Li… - Science China …, 2024 - Springer
Supramolecular systems feature dynamic, reversible and stimuli-responsive characteristics,
which are not easily achieved by molecular entities. The last decade has witnessed …