Intestinal Fibrogenesis in Inflammatory Bowel Diseases: Exploring the Potential Role of Gut Microbiota Metabolites as Modulators
S Cicchinelli, S Gemma, G Pignataro, A Piccioni… - Pharmaceuticals, 2024 - mdpi.com
Fibrosis, sustained by the transformation of intestinal epithelial cells into fibroblasts
(epithelial-to-mesenchymal transition, EMT), has been extensively studied in recent …
(epithelial-to-mesenchymal transition, EMT), has been extensively studied in recent …
Mesenchymal Stem Cells and Purinergic Signaling in Autism Spectrum Disorder: Bridging the Gap between Cell-Based Strategies and Neuro-Immune Modulation
A Wikarska, K Roszak, K Roszek - Biomedicines, 2024 - mdpi.com
The prevalence of autism spectrum disorder (ASD) is still increasing, which means that this
neurodevelopmental lifelong pathology requires special scientific attention and efforts …
neurodevelopmental lifelong pathology requires special scientific attention and efforts …
Extracellular histones promote TWIK2-dependent potassium efflux and associated NLRP3 activation in alveolar macrophages during sepsis-induced lung injury
J Yu, Y Fu, N Zhang, J Gao, Z Zhang, X Jiang… - Inflammation …, 2024 - Springer
Methods and results We conducted experiments using cecal ligation and puncture (CLP)
C57BL/6 mice and extracellular histone-stimulated LPS-primed MH-S cells. The results …
C57BL/6 mice and extracellular histone-stimulated LPS-primed MH-S cells. The results …
Using the Traditional Ex Vivo Whole Blood Model to Discriminate Bacteria by Their Inducible Host Responses
HM Chick, ME Rees, ML Lewis, LK Williams, O Bodger… - Biomedicines, 2024 - mdpi.com
Whole blood models are rapid and versatile for determining immune responses to
inflammatory and infectious stimuli, but they have not been used for bacterial discrimination …
inflammatory and infectious stimuli, but they have not been used for bacterial discrimination …
Targeting the Nlrp3 inflammasome as potential treatment for ethanol-induced non-communicable diseases
PD Drew - The American Journal of Drug and Alcohol Abuse, 2024 - Taylor & Francis
The innate immune system plays a protective role through the expression of pattern
recognition receptors (PRRs), which recognize pathogen-associated molecular patterns …
recognition receptors (PRRs), which recognize pathogen-associated molecular patterns …
Evolving Paradigms in Sepsis Management: A Narrative Review
MJ Kim, EJ Choi, EJ Choi - Cells, 2024 - mdpi.com
Sepsis, a condition characterized by life-threatening organ dysfunction due to a
dysregulated host response to infection, significantly impacts global health, with mortality …
dysregulated host response to infection, significantly impacts global health, with mortality …
Navigating the Modern Landscape of Sepsis: Advances in Diagnosis and Treatment
JH Jang, E Choi, T Kim, HJ Yeo, D Jeon… - International Journal of …, 2024 - mdpi.com
Sepsis poses a significant threat to human health due to its high morbidity and mortality
rates worldwide. Traditional diagnostic methods for identifying sepsis or its causative …
rates worldwide. Traditional diagnostic methods for identifying sepsis or its causative …
[PDF][PDF] Significance of Host Defence Genetics Initiative in Pneumonia
T Mariam, A Saleem, M Shahzad, AA Baig - 2024 - researchgate.net
Pneumonia, a prevalent and life-threatening respiratory infection, continues to pose a
significant global health challenge. This article provides a comprehensive review of recent …
significant global health challenge. This article provides a comprehensive review of recent …
Antibiotic therapy in septic patients treated with renal replacement and extracorporeal blood purification therapy
AF Schelling - 2024 - zir.nsk.hr
Sažetak Introduction: Sepsis accounts for one of the leading causes of death in critically ill
patients in the ICU. One of the most common and severe complications of sepsis is acute …
patients in the ICU. One of the most common and severe complications of sepsis is acute …