Inflammation and Alzheimer's disease

H Akiyama, S Barger, S Barnum, B Bradt, J Bauer… - Neurobiology of …, 2000 - Elsevier
Inflammation clearly occurs in pathologically vulnerable regions of the Alzheimer's disease
(AD) brain, and it does so with the full complexity of local peripheral inflammatory responses …

Cyclooxygenase isozymes: the biology of prostaglandin synthesis and inhibition

DL Simmons, RM Botting, T Hla - Pharmacological reviews, 2004 - ASPET
Nonsteroidal anti-inflammatory drugs (NSAIDs) represent one of the most highly utilized
classes of pharmaceutical agents in medicine. All NSAIDs act through inhibiting …

[HTML][HTML] Antioxidant and anti-inflammatory activities of zinc oxide nanoparticles synthesized using Polygala tenuifolia root extract

PC Nagajyothi, SJ Cha, IJ Yang, TVM Sreekanth… - … of Photochemistry and …, 2015 - Elsevier
The exploitation of various plant materials for the green synthesis of nanoparticles is
considered an eco-friendly technology because it does not involve toxic chemicals. In this …

Neuroprotective effect of quercetin against the detrimental effects of LPS in the adult mouse brain

A Khan, T Ali, SU Rehman, MS Khan, SI Alam… - Frontiers in …, 2018 - frontiersin.org
Chronic neuroinflammation is responsible for multiple neurodegenerative diseases, such as
Alzheimer's disease, Parkinson's disease, and Huntington's disease. Lipopolysaccharide …

Cardiac endothelial-myocardial signaling: its role in cardiac growth, contractile performance, and rhythmicity

DL Brutsaert - Physiological reviews, 2003 - journals.physiology.org
Experimental work during the past 15 years has demonstrated that endothelial cells in the
heart play an obligatory role in regulating and maintaining cardiac function, in particular, at …

Role of nitric oxide in the biology, physiology and pathophysiology of reproduction

M Rosselli, RJ Keller, RK Dubey - Human reproduction update, 1998 - academic.oup.com
Following its benchmark discovery, nitric oxide (NO) is now known to play important
functional roles in a variety of physiological systems. Within the vasculature, NO induces …

Pain and analgesia: The dual effect of nitric oxide in the nociceptive system

Y Cury, G Picolo, VP Gutierrez, SH Ferreira - Nitric oxide, 2011 - Elsevier
Nitric oxide (NO) is involved in many physiological processes and several lines of evidence
have indicated that NO plays a complex and diverse role in the modulation of pain. Nitric …

cellular and molecular mechanisms of NSAID‐induced peptic ulcers

C Musumba, DM Pritchard… - Alimentary …, 2009 - Wiley Online Library
Background Nonsteroidal anti‐inflammatory drugs (NSAIDs) are some of the most
prescribed drugs worldwide and have now probably overtaken Helicobacter pylori as the …

Biology of nitric oxide signaling

L Liaudet, FG Soriano, C Szabó - Critical care medicine, 2000 - journals.lww.com
The free radical nitric oxide (NO) has emerged in recent years as a fundamental signaling
molecule for the maintenance of homeostasis, as well as a potent cytotoxic effector involved …

Evidence that Alzheimer's disease is a microvascular disorder: the role of constitutive nitric oxide

JC De la Torre, GB Stefano - Brain research reviews, 2000 - Elsevier
Evidence is fast accumulating which indicates that Alzheimer's disease is a vascular
disorder with neurodegenerative consequences rather than a neurodegenerative disorder …