Is oxytocin “nature's medicine”?

CS Carter, WM Kenkel, EL MacLean, SR Wilson… - Pharmacological …, 2020 - ASPET
Oxytocin is a pleiotropic, peptide hormone with broad implications for general health,
adaptation, development, reproduction, and social behavior. Endogenous oxytocin and …

Advances in stroke pharmacology

Z Zhou, J Lu, WW Liu, A Manaenko, X Hou… - Pharmacology & …, 2018 - Elsevier
Stroke occurs when a cerebral blood vessel is blocked or ruptured, and it is the major cause
of death and adult disability worldwide. Various pharmacological agents have been …

The role of oxytocin in cardiovascular protection

M Jankowski, TL Broderick, J Gutkowska - Frontiers in psychology, 2020 - frontiersin.org
The beneficial effects of oxytocin on infarct size and functional recovery of the ischemic
reperfused heart are well documented. The mechanisms for this cardioprotection are not …

Neuropeptides: Potential neuroprotective agents in ischemic injury

P Saklani, H Khan, S Gupta, A Kaur, TG Singh - Life Sciences, 2022 - Elsevier
Aim Ischemic damage to the brain is linked to an increased rate of morbidity and mortality
worldwide. In certain parts of the world, it remains a leading cause of mortality and the …

Oxytocin and oxygen: the evolution of a solution to the 'stress of life'

CS Carter, MA Kingsbury - Philosophical Transactions of …, 2022 - royalsocietypublishing.org
Oxytocin (OT) and the OT receptor occupy essential roles in our current understanding of
mammalian evolution, survival, sociality and reproduction. This narrative review examines …

[HTML][HTML] Revealing the neurobiology underlying interpersonal neural synchronization with multimodal data fusion

LD Lotter, SH Kohl, C Gerloff, L Bell, A Niephaus… - … & biobehavioral reviews, 2023 - Elsevier
Humans synchronize with one another to foster successful interactions. Here, we use a
multimodal data fusion approach with the aim of elucidating the neurobiological …

The inflammatory event of birth: How oxytocin signaling may guide the development of the brain and gastrointestinal system

MA Kingsbury, SD Bilbo - Frontiers in Neuroendocrinology, 2019 - Elsevier
The role of oxytocin (OT) as a neuropeptide that modulates social behavior has been
extensively studied and reviewed, but beyond these functions, OT's adaptive functions at …

[HTML][HTML] Oxytocin improves animal behaviors and ameliorates oxidative stress and inflammation in autistic mice

Y Wang, S Zhao, X Liu, Y Zheng, L Li… - Biomedicine & …, 2018 - Elsevier
Objective Autism is a neurodevelopmental disorder which significantly impacts the quality of
people's life. Oxytocin is a hormone impacting the social cognition and interpersonal trust. In …

Nanomedicines, an emerging therapeutic regimen for treatment of ischemic cerebral stroke: A review

W Chen, L Jiang, Y Hu, G Fang, B Yang, J Li… - Journal of Controlled …, 2021 - Elsevier
Owing to its intricate pathophysiology, cerebral stroke is a serious medical condition caused
by interruption or obstruction of blood supply (blockage of vasculature) to the brain tissues …

Oxytocin functions as a spatiotemporal filter for excitatory synaptic inputs to VTA dopamine neurons

L Xiao, MF Priest, Y Kozorovitskiy - Elife, 2018 - elifesciences.org
The experience of rewarding or aversive stimuli is encoded by distinct afferents to dopamine
(DA) neurons of the ventral tegmental area (VTA). Several neuromodulatory systems …