[HTML][HTML] Prognostic gene signature for squamous cell carcinoma with a higher risk for treatment failure and accelerated MEK-ERK pathway activity

B Feng, K Wang, E Herpel, M Plath, W Weichert… - Cancers, 2021 - mdpi.com
Simple Summary Squamous cell carcinoma (SCC) is the most prevalent type of human
cancer worldwide and represents the majority of head and neck tumors. As SCC from …

[HTML][HTML] Promoter DNA methylation patterns in oral, laryngeal and oropharyngeal anatomical regions are associated with tumor differentiation, nodal involvement and …

B Rivera-Peña, O Folawiyo, N Turaga… - Oncology …, 2024 - spandidos-publications.com
Differentially methylated regions (DMRs) can be used as head and neck squamous cell
carcinoma (HNSCC) diagnostic, prognostic and therapeutic targets in precision medicine …

Upregulated miR-125b mitigates inflammation, astrocyte activation, and dysfunction of spinal cord injury by inactivating the MAPK pathway

X Yue, M Gu, T Jia - 2024 - digitum.um.es
Background. Since the abnormal expression of miR-125b in spinal cord injury (SCI) and the
regulatory effect of miR-125b on the MAPK pathway have been expounded, we attempt to …

Copper‐Related Cell Death and the Role of Copper in Head and Neck Squamous Cell Carcinoma and Therapeutic Strategies

Z Zhang, Y Wu, S Wang, G Wang, H Zhang… - Advanced …, 2024 - Wiley Online Library
As an essential mineral element for the human body, copper (Cu) is necessary for various
physiological functions. Excess or deficiency of copper causes cytotoxicity and damages the …

[HTML][HTML] Rational combinations of targeted therapy and immune checkpoint inhibitors in head and neck cancers

AWY Chai, PS Yee, SC Cheong - Frontiers in Oncology, 2022 - frontiersin.org
Immunotherapy, especially the immune checkpoint inhibitors (ICIs) such as the
pembrolizumab and nivolumab have contributed to significant improvements in treatment …

Metastatic patterns and treatment options for head and neck cutaneous squamous cell carcinoma

D Iancu, A Fulga, D Vesa… - Molecular and …, 2024 - spandidos-publications.com
According to current predictions, one‑fifth of all Americans will develop skin cancer during
their lifetime. Cutaneous squamous cell carcinoma (cSCC) most commonly occurs in the …

[PDF][PDF] Investigating EGFR, BRAF, and RAS Mutations in Oral and Cutaneous Squamous Cell Neoplasms: A Preliminary Report on Romanian Patients

EG Dobre, A Căruntu, AN Munteanu… - … Journal of Military …, 2024 - revistamedicinamilitara.ro
Background: Head and neck cancers, and particularly, oral cancers have a complex
pathogenesis that includes genetic mutations and epigenetic alterations which interfere with …

Identification and Analysis of Immune Microenvironment-Related Genes for Keloid Risk Prediction and Their Effects on Keloid Proliferation and Migration

Y Pei, Y Wu, M Zhang, X Su, H Cao, J Zhao - Biochemical Genetics, 2023 - Springer
Keloid is a kind of proliferative scar with continuous growth, no restriction and easy
recurrence, which cannot be cured and bring serious physical injury and psychological …

[HTML][HTML] Comprehensive exome analysis of immunocompetent metastatic head and neck cancer models reveals patient relevant landscapes

H Li, HL Ngan, Y Liu, HHY Chan, PHY Poon… - Cancers, 2020 - mdpi.com
Simple Summary Head and neck cancer (HNC), once metastasized, is very difficult to treat
as there are limited therapy options. Animal models of such can be very useful for preclinical …

[HTML][HTML] Identification of metabolic signatures related to metastasis and immunotherapy resistance in oral squamous cell carcinoma

H Chen, X Liu, F Yao, M Yin, B Cheng… - American Journal of …, 2023 - ncbi.nlm.nih.gov
Objectives: In this study, we aimed to identify the metabolic genes associated with the
metastasis and immunotherapy resistance of oral squamous cell carcinoma (OSCC) and to …