Background Sodium–glucose cotransporter 2 (SGLT2) inhibitors constitute the gold
standard treatment for type 2 diabetes mellitus (T2DM). Among them, empagliflozin (EMPA) …

Protein glycosylation is an extensively studied field, with the most studied forms being
oxygen or nitrogen-linked N-acetylglucosamine (O-GlcNAc or N-GlcNAc) glycosylation …

The indolamine hormone melatonin, also known as N-acetyl-5-methoxytrypamine, is
frequently associated with circadian rhythm regulation. Light can suppress melatonin …

The increasing incidence of diabetes has prompted the need for new treatment strategies,
including natural products that reduce glycemia values. This work examined the in vitro and …

Background Oral leukoplakia (OLK), characterized by abnormal epithelial hyperplasia, is the
most common precancerous oral mucosa lesion and is closely related to oxidative stress …

Carvedilol (CVD), an adrenoreceptor blocker, is a hydrophobic Biopharmaceutics
Classification System class II drug with poor oral bioavailability due to which frequent dosing …

Background Mitochondrial alterations, often dependent on unbalanced mitochondrial
dynamics, feature in the pathobiology of human cancers, including multiple myeloma (MM) …

Maladaptive cardiac hypertrophy contributes to the development of heart failure (HF). The
oxidoreductase Selenoprotein T (SELENOT) emerged as a key regulator during rat …

Background Chinese visceral adiposity index (CVAI) is a reliable visceral obesity index, but
the association between CVAI and risk of cardiovascular disease (CVD) remains unclear …

Objectives: We conducted an assessment to explore potential associations of the dietary
oxidative balance score (DOBS), cardiovascular disease (CVD), with all-cause mortality …