Pathogenesis and management of abdominal aortic aneurysm

J Golledge, S Thanigaimani, JT Powell… - European Heart …, 2023 - academic.oup.com
Abdominal aortic aneurysm (AAA) causes∼ 170 000 deaths annually worldwide. Most
guidelines recommend asymptomatic small AAAs (30 to< 50 mm in women; 30 to< 55 mm in …

[HTML][HTML] Blood pressure, hypertension and the risk of abdominal aortic aneurysms: a systematic review and meta-analysis of cohort studies

E Kobeissi, M Hibino, H Pan, D Aune - European journal of epidemiology, 2019 - Springer
Abdominal aortic aneurysms (AAA) are fatal in 80% of the cases when ruptured.
Hypertension has been considered a potential risk factor for AAA; but the findings from …

Metformin prescription and aortic aneurysm: systematic review and meta-analysis

X Yu, D Jiang, J Wang, R Wang, T Chen, K Wang… - Heart, 2019 - heart.bmj.com
Objective To assess the association of metformin prescription with the risk of aortic
aneurysm, aortic aneurysm events and the enlargement of abdominal aortic aneurysm …

Abdominal aortic aneurysms (etiology, epidemiology, and natural history)

MP Calgi, JS McNeil - Anesthesiology clinics, 2022 - anesthesiology.theclinics.com
The abdominal aorta is the portion of the descending aorta between the diaphragm and the
common iliac artery bifurcation. A retroperitoneal structure, it courses through the diaphragm …

[HTML][HTML] Physical activity and the risk of abdominal aortic aneurysm: a systematic review and meta-analysis of prospective studies

D Aune, A Sen, E Kobeissi, M Hamer, T Norat… - Scientific reports, 2020 - nature.com
The association between physical activity and risk of abdominal aortic aneurysm has been
inconsistent with some studies reporting a reduced risk while others have found no …

[HTML][HTML] Type 2 diabetes has a protective causal association with thoracic aortic aneurysm: a Mendelian randomization study

Y Zhang, Y Li, X Dai, H Lin, L Ma - Diabetology & Metabolic Syndrome, 2023 - Springer
Background Observational studies have reported an inverse association of type 2 diabetes
(T2D) with thoracic aortic aneurysm (TAA). However, the causality of the association has not …

[HTML][HTML] Systematic review and meta-analysis of Mendelian randomisation analyses of abdominal aortic aneurysms

M Ibrahim, S Thanigaimani, TP Singh, D Morris… - IJC Heart & …, 2021 - Elsevier
Introduction Mendelian randomisation (MR) has been suggested to be able to overcome
biases of observational studies, but no meta-analysis is available on MR studies on …

[HTML][HTML] Insulin resistance promotes the formation of aortic dissection by inducing the phenotypic switch of vascular smooth muscle cells

H Zheng, Z Qiu, T Chai, J He, Y Zhang… - Frontiers in …, 2022 - frontiersin.org
Background Insulin resistance (IR) plays a key role in the development of type 2 diabetes
mellitus (T2DM) and is one of its most important characteristics. Previous studies have …

Diabetes, its duration, and the long-term risk of abdominal aortic aneurysm: The Atherosclerosis Risk in Communities (ARIC) Study

X Ning, N Ding, SH Ballew, CW Hicks, J Coresh… - Atherosclerosis, 2020 - Elsevier
Background and aims We aimed at comprehensively evaluate the independent association
of diabetes and its duration with incident abdominal aortic aneurysm (AAA) and aortic …

Diabetes Mellitus and Noncardiac Atherosclerotic Vascular Disease—Pathogenesis and Pharmacological Treatment Options

EM Muzurović, DP Mikhailidis - Journal of Cardiovascular …, 2021 - journals.sagepub.com
Diabetes mellitus (DM) is also a cause of cardiovascular (CV) disease (CVD). Addressing
the atherosclerotic CVD (ASCVD) burden in DM should reduce premature death and …