Epstein–Barr virus and multiple sclerosis

SS Soldan, PM Lieberman - Nature Reviews Microbiology, 2023 - nature.com
Epstein–Barr virus (EBV) is a ubiquitous human lymphotropic herpesvirus with a well-
established causal role in several cancers. Recent studies have provided compelling …

Epstein Barr virus: development of vaccines and immune cell therapy for EBV-associated diseases

X Cui, CM Snapper - Frontiers in Immunology, 2021 - frontiersin.org
Epstein-Barr virus (EBV) is the first human tumor virus discovered and is strongly implicated
in the etiology of multiple lymphoid and epithelial cancers. Each year EBV associated …

Longitudinal analysis reveals high prevalence of Epstein-Barr virus associated with multiple sclerosis

K Bjornevik, M Cortese, BC Healy, J Kuhle, MJ Mina… - Science, 2022 - science.org
Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central
nervous system of unknown etiology. We tested the hypothesis that MS is caused by Epstein …

Epstein–Barr virus and cancer

PJ Farrell - Annual Review of Pathology: Mechanisms of …, 2019 - annualreviews.org
Epstein–Barr virus (EBV) contributes to about 1.5% of all cases of human cancer worldwide,
and viral genes are expressed in the malignant cells. EBV also very efficiently causes the …

Primary epstein-barr virus infection

SK Dunmire, PS Verghese, HH Balfour Jr - Journal of Clinical Virology, 2018 - Elsevier
Epstein-Barr virus (EBV) infects about 90% of adults worldwide. It is the main cause of
infectious mononucleosis, which is observed most frequently in adolescents. The disease …

Progressive multiple sclerosis: from pathogenic mechanisms to treatment

J Correale, MI Gaitán, MC Ysrraelit, MP Fiol - Brain, 2017 - academic.oup.com
During the past decades, better understanding of relapsing-remitting multiple sclerosis
disease mechanisms have led to the development of several disease-modifying therapies …

Off-the-shelf virus-specific T cells to treat BK virus, human herpesvirus 6, cytomegalovirus, Epstein-Barr virus, and adenovirus infections after allogeneic hematopoietic …

I Tzannou, A Papadopoulou, S Naik… - Journal of Clinical …, 2017 - ascopubs.org
Purpose Improvement of cure rates for patients treated with allogeneic hematopoietic stem-
cell transplantation (HSCT) will require efforts to decrease treatment-related mortality from …

Epstein–Barr virus-associated lymphomas

C Shannon-Lowe, AB Rickinson… - … Transactions of the …, 2017 - royalsocietypublishing.org
Epstein–Barr virus (EBV), originally discovered through its association with Burkitt
lymphoma, is now aetiologically linked to a remarkably wide range of lymphoproliferative …

Ectopic lymphoid-like structures in infection, cancer and autoimmunity

C Pitzalis, GW Jones, M Bombardieri… - Nature Reviews …, 2014 - nature.com
Ectopic lymphoid-like structures often develop at sites of inflammation where they influence
the course of infection, autoimmune disease, cancer and transplant rejection. These …

The immunology of Epstein-Barr virus–induced disease

GS Taylor, HM Long, JM Brooks… - Annual review of …, 2015 - annualreviews.org
Epstein-Barr virus (EBV) is usually acquired silently early in life and carried thereafter as an
asymptomatic infection of the B lymphoid system. However, many circumstances disturb the …