Muscle metabolism and atrophy: let's talk about sex

ME Rosa-Caldwell, NP Greene - Biology of sex differences, 2019 - Springer
Skeletal muscle health is a strong predictor of overall health and longevity. Pathologies
affecting skeletal muscle such as cancer cachexia, intensive care unit treatment, muscular …

Evolving roles of muscle-resident fibro-adipogenic progenitors in health, regeneration, neuromuscular disorders, and aging

M Theret, FMV Rossi, O Contreras - Frontiers in Physiology, 2021 - frontiersin.org
Normal skeletal muscle functions are affected following trauma, chronic diseases, inherited
neuromuscular disorders, aging, and cachexia, hampering the daily activities and quality of …

[PDF][PDF] Muscle satellite cell cross-talk with a vascular niche maintains quiescence via VEGF and notch signaling

M Verma, Y Asakura, BSR Murakonda, T Pengo… - Cell stem cell, 2018 - cell.com
Skeletal muscle is a complex tissue containing tissue resident muscle stem cells (satellite
cells)(MuSCs) important for postnatal muscle growth and regeneration. Quantitative analysis …

Degenerative and regenerative pathways underlying Duchenne muscular dystrophy revealed by single-nucleus RNA sequencing

F Chemello, Z Wang, H Li… - Proceedings of the …, 2020 - National Acad Sciences
Duchenne muscular dystrophy (DMD) is a fatal muscle disorder characterized by cycles of
degeneration and regeneration of multinucleated myofibers and pathological activation of a …

[HTML][HTML] Constitutive activities of estrogen-related receptors: Transcriptional regulation of metabolism by the ERR pathways in health and disease

JM Huss, WG Garbacz, W Xie - … et Biophysica Acta (BBA)-Molecular Basis …, 2015 - Elsevier
The estrogen-related receptors (ERRs) comprise a small group of orphan nuclear receptor
transcription factors. The ERRα and ERRγ isoforms play a central role in the regulation of …

[HTML][HTML] Superficial and deep changes of histology, texture and particle size distribution in broiler wooden breast muscle during refrigerated storage

F Soglia, J Gao, M Mazzoni, E Puolanne, C Cavani… - Poultry Science, 2017 - Elsevier
Recently the poultry industry faced an emerging muscle abnormality termed wooden breast
(WB), the prevalence of which has dramatically increased in the past few years. Considering …

ERRγ: a junior orphan with a senior role in metabolism

J Misra, DK Kim, HS Choi - Trends in Endocrinology & Metabolism, 2017 - cell.com
Estrogen-related receptor (ERR) γ is an orphan nuclear hormone receptor that belongs to
the ERR subfamily of transcription factors. No endogenous ligand has been identified to …

AMPK is mitochondrial medicine for neuromuscular disorders

AI Mikhail, SY Ng, SR Mattina, V Ljubicic - Trends in Molecular Medicine, 2023 - cell.com
Duchenne muscular dystrophy (DMD), myotonic dystrophy type 1 (DM1), and spinal
muscular atrophy (SMA) are the most prevalent neuromuscular disorders (NMDs) in children …

Role of hypoxia in skeletal muscle fibrosis: Synergism between hypoxia and TGF-β signaling upregulates CCN2/CTGF expression specifically in muscle fibers

R Valle-Tenney, DL Rebolledo, KE Lipson, E Brandan - Matrix Biology, 2020 - Elsevier
Several skeletal muscle diseases are characterized by fibrosis, the excessive accumulation
of extracellular matrix. Transforming growth factor-β (TGF-β) and connective tissue growth …

Resveratrol induces expression of the slow, oxidative phenotype in mdx mouse muscle together with enhanced activity of the SIRT1-PGC-1α axis

V Ljubicic, M Burt, JA Lunde… - American Journal of …, 2014 - journals.physiology.org
Slower, more oxidative muscle fibers are more resistant to the dystrophic pathology in
Duchenne muscular dystrophy (DMD) patients as well as in the preclinical mdx mouse …