Antifungal Drug Resistance: Molecular Mechanisms in Candida albicans and Beyond
Fungal infections are a major contributor to infectious disease-related deaths across the
globe. Candida species are among the most common causes of invasive mycotic disease …
globe. Candida species are among the most common causes of invasive mycotic disease …
[HTML][HTML] Antifungal drug resistance: an emergent health threat
A Vitiello, F Ferrara, M Boccellino, A Ponzo, C Cimmino… - Biomedicines, 2023 - mdpi.com
Fungal infections, named mycosis, can cause severe invasive and systemic diseases that
can even lead to death. In recent years, epidemiological data have recorded an increase in …
can even lead to death. In recent years, epidemiological data have recorded an increase in …
[HTML][HTML] Fungal infections in humans: the silent crisis
Annually, over 150 million severe cases of fungal infections occur worldwide, resulting in
approximately 1.7 million deaths per year. Alarmingly, these numbers are continuously on …
approximately 1.7 million deaths per year. Alarmingly, these numbers are continuously on …
[HTML][HTML] Ten decadal advances in fungal biology leading towards human well-being
Fungi are an understudied resource possessing huge potential for developing products that
can greatly improve human well-being. In the current paper, we highlight some important …
can greatly improve human well-being. In the current paper, we highlight some important …
[PDF][PDF] Hope on the horizon: novel fungal treatments in development
AM Rauseo, A Coler-Reilly, L Larson… - Open Forum Infectious …, 2020 - academic.oup.com
The treatment of invasive fungal infections remains challenging due to limitations in currently
available antifungal therapies including toxicity, interactions, restricted routes of …
available antifungal therapies including toxicity, interactions, restricted routes of …
[HTML][HTML] Primary prophylaxis of invasive fungal infections in patients with haematological malignancies: 2017 update of the recommendations of the Infectious …
SC Mellinghoff, J Panse, N Alakel, G Behre… - Annals of …, 2018 - Springer
Immunocompromised patients are at high risk of invasive fungal infections (IFI), in particular
those with haematological malignancies undergoing remission-induction chemotherapy for …
those with haematological malignancies undergoing remission-induction chemotherapy for …
[HTML][HTML] Essential oils and their natural active compounds presenting antifungal properties
M D'agostino, N Tesse, JP Frippiat, M Machouart… - Molecules, 2019 - mdpi.com
The current rise in invasive fungal infections due to the increase in immunosuppressive
therapies is a real concern. Moreover, the emergence of resistant strains induces …
therapies is a real concern. Moreover, the emergence of resistant strains induces …
Epidemiology and clinical features of invasive fungal infection in a US health care network
BJ Webb, JP Ferraro, S Rea, S Kaufusi… - Open forum …, 2018 - academic.oup.com
Background A better understanding of the epidemiology and clinical features of invasive
fungal infection (IFI) is integral to improving outcomes. We describe a novel case-finding …
fungal infection (IFI) is integral to improving outcomes. We describe a novel case-finding …
[HTML][HTML] Lipid systems for the delivery of amphotericin B in antifungal therapy
C Faustino, L Pinheiro - Pharmaceutics, 2020 - mdpi.com
Amphotericin B (AmB), a broad-spectrum polyene antibiotic in the clinic for more than fifty
years, remains the gold standard in the treatment of life-threatening invasive fungal …
years, remains the gold standard in the treatment of life-threatening invasive fungal …
Adverse effects associated with long-term administration of azole antifungal agents
LL Benitez, PL Carver - Drugs, 2019 - Springer
Azole antifungals are first-line options in the prophylaxis and treatment of invasive fungal
infections. They are often used for prolonged (weeks to months) periods of time, particularly …
infections. They are often used for prolonged (weeks to months) periods of time, particularly …