Most chronic inflammatory illnesses include fibrosis as a pathogenic characteristic.
Extracellular matrix (ECM) components build up in excess to cause fibrosis or scarring. The …

Oxidative stress is a major component of cell damage and cell fat, and as such, it occupies a
central position in the pathogenesis of metabolic disease. Nuclear factor-erythroid-derived 2 …

In many organisms, cytochrome P450 enzymes are the primary detoxifying enzymes.
Enhanced P450 activity can be mediated by the emergence of new genes, increased …

Diagnosis and cure for rare diseases represent a great challenge for the scientific
community who often comes up against the complexity and heterogeneity of clinical picture …

The rapid growth of vascular smooth muscle cells (VSMCs) represents crucial pathological
changes during the development of hypertensive vascular remodeling. Although quercetin …

Neurodegenerative diseases (NDDs) are a collection of incapacitating disorders in which
neuroinflammation and neuronal apoptosis are major pathological consequences due to …

Background In kidney transplant recipients (KTRs) who are immunosuppressed, human BK
polyomavirus (BKPyV) infection can be reactivated, resulting in BKPyV-associated …

Cadmium (Cd) is one of the most abundant toxic heavy metals, and its exposure is linked to
serious kidney intoxication, a major health problem. Evidence reported that inflammatory …

Objective To observe the effect of Shenbing Decoction Ⅲ for improving renal function and
pathology in rats with 5/6 nephrectomy and analyze its therapeutic mechanism for renal …

肾病Ⅲ号方治疗慢性肾脏病大鼠肾脏纤维化的作用机制: 基于网络药理学和分子对接技术- PMC
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