Impact of cytomegalovirus infection on organ transplant recipients

RH Rubin - Reviews of infectious diseases, 1990 - academic.oup.com
Cytomegalovirus (CMV) is the single most important infectious agent affecting recipients of
organ transplants, with at least two-thirds of these patients having CMV infection 1–4 months …

[HTML][HTML] Antigens and immunoevasins: opponents in cytomegalovirus immune surveillance

MJ Reddehase - Nature Reviews Immunology, 2002 - nature.com
CD8+ T cells are the main effector cells for the immune control of cytomegaloviruses. To
subvert this control, human and mouse cytomegaloviruses each encode a set of immune …

Site-restricted persistent cytomegalovirus infection after selective long-term depletion of CD4+ T lymphocytes.

S Jonjić, W Mutter, F Weiland, MJ Reddehase… - The Journal of …, 1989 - rupress.org
We have established a murine model system for exploring the ability of a CD4 subset-
deficient host to cope with cytomegalovirus infection, and reported three findings. First, an …

CD8-positive T lymphocytes specific for murine cytomegalovirus immediate-early antigens mediate protective immunity

MJ Reddehase, W Mutter, K Münch, HJ Bühring… - Journal of …, 1987 - Am Soc Microbiol
We have shown in a murine model system for acute, lethal cytomegalovirus (CMV) disease
in the immunocompromised natural host that control of virus multiplication in tissues …

Interstitial murine cytomegalovirus pneumonia after irradiation: characterization of cells that limit viral replication during established infection of the lungs

MJ Reddehase, F Weiland, K Münch, S Jonjic… - Journal of …, 1985 - Am Soc Microbiol
Interstitial pneumonia associated with viral replication in lung tissue was observed after
cytomegalovirus infection of total-body gamma-irradiated mice, whereas in …

Identification of the major late human cytomegalovirus matrix protein pp65 as a target antigen for CD8+ virus‐specific cytotoxic T lymphocytes

E McLaughlin‐Taylor, H Pande… - Journal of medical …, 1994 - Wiley Online Library
Primary Cytomegalovirus (CMV) infection and reactivation of persistent CMV are associated
with significant morbidity and mortality in immuno‐compromised individuals. Although …

A pentapeptide as minimal antigenic determinant for MHC class I-restricted T lymphocytes

MJ Reddehase, JB Rothbard, UH Koszinowski - Nature, 1989 - nature.com
Peptides that are antigenic for T lymphocytes are ligands for two receptors, the class I or II
glycoproteins that are encoded by genes in the major histocompatibility complex, and the …

Efficacious control of cytomegalovirus infection after long-term depletion of CD8+ T lymphocytes

S Jonjić, I Pavić, P Lucin, D Rukavina… - Journal of …, 1990 - Am Soc Microbiol
Although the relative contribution of different immune effector functions to clearing tissues of
cytomegalovirus is controversial, the contribution of CD8+ T lymphocytes has generally …

Gamma interferon-dependent clearance of cytomegalovirus infection in salivary glands

P Lucin, I Pavić, B Polić, S Jonjić… - Journal of …, 1992 - Am Soc Microbiol
Cytomegalovirus (CMV), similar to other members of the Herpesviridae family, can establish
both persistent and latent infections. Each of the CMVs that are found in many animal …

Enrichment of Immediate-Early 1 (m123/pp89) Peptide-Specific CD8 T Cells in a Pulmonary CD62Llo Memory-Effector Cell Pool during Latent Murine …

R Holtappels, MF Pahl-Seibert, D Thomas… - Journal of …, 2000 - Am Soc Microbiol
Interstitial cytomegalovirus (CMV) pneumonia is a clinically relevant complication in
recipients of bone marrow transplantation (BMT). Recent data for a model of experimental …