Aims: To examine the causes of variability in the effect of maternal drinking on the foetus,
with particular reference to the pattern, frequency and duration of the period of drinking …

Excessive drinking can damage brain tissue and cause cognitive dysfunction. Studies have
found that the early stage of neurodegenerative disease is closely related to heavy drinking …

Although significant progress has been made in protein quantification using mass
spectrometry during recent years, absolute protein quantification in complex biological …

Background Although hypersensitivity reactions following intake of alcoholic drinks are
common in Caucasians, the underlying mechanisms and clinical significance are not known …

Abstract α-Linolenic acid (ALA), a major fatty acid in flaxseed oil, has multiple functionalities
such as anti-cardiovascular and anti-hypertensive activities. In this study, we investigated …

AIM: To evaluate the association between genetic polymorphisms in CYP2E1, ALDH2 and
ADH1B and the risk of esophageal squamous cell carcinoma (ESCC) in a high risk area of …

Background: Genetic variation in ethanol metabolism may have an influence on both alcohol
drinking habits and the susceptibility to health effects of alcohol drinking. Such influences …

Drug side effects and toxicity and often the drug efficacy are highly dependent on drug
metabolism determining the activation and/or elimination of the respective compound. In …

BACKGROUND: Alcohol consumption during pregnancy is known to be associated with
certain birth defects, but the risk of other birth defects is less certain. The authors examined …

Aims: The present study explored whether specific single-nucleotide polymorphisms in
alcohol metabolic pathway are associated with alcohol dependence or alcohol-related …