Alcohol induced impairment/abnormalities in brain: role of microRNAs

A Divakar, S Kanchan, G Jha, S Mishra, D Sharma… - Neurotoxicology, 2021 - Elsevier
Alcohol is a highly toxic substance and has teratogenic properties that can lead to a wide
range of developmental disorders. Excessive use of alcohol can change the structural and …

Alcohol and the liver

A Reuben - Current opinion in gastroenterology, 2007 - journals.lww.com
Alcohol and the liver : Current Opinion in Gastroenterology Alcohol and the liver : Current
Opinion in Gastroenterology Log in or Register Subscribe to journalSubscribe Get new issue …

Genetic Polymorphisms of Genes Coding to Alcohol‐Metabolizing Enzymes in Western Mexicans: Association of CYP2E1*c2/CYP2E1*5B Allele with Cirrhosis and …

J García‐Bañuelos, A Panduro… - Alcoholism: Clinical …, 2012 - Wiley Online Library
Background: Alcoholic cirrhosis constitutes a major public health problem in the world where
ADH1B, ALDH2, and CYP2E1 polymorphisms could be playing an important role. We …

Chronic exposure to ethanol exacerbates MDMA-induced hyperthermia and exposes liver to severe MDMA-induced toxicity in CD1 mice

H Pontes, JA Duarte, PG de Pinho, ME Soares… - Toxicology, 2008 - Elsevier
3, 4-Methylenedioxymethamphetamine (MDMA; ecstasy) is an amphetamine derivative drug
with entactogenic, empathogenic and hallucinogenic properties, commonly consumed at …

Drinking motives and college alcohol problems: A prospective study

PM Vernig, SM Orsillo - Journal of Substance Use, 2015 - Taylor & Francis
Alcohol misuse among college students is well-documented, and cross-sectional research
has identified attempts to cope with unpleasant emotions, enhance pleasant emotions …

[HTML][HTML] Polymorphisms of alcohol dehydrogenase-2 and aldehyde dehydrogenase-2 and esophageal cancer risk in Southeast Chinese males

JH Ding, SP Li, HX Cao, JZ Wu, CM Gao… - World Journal of …, 2009 - ncbi.nlm.nih.gov
AIM: To evaluate the impact of alcohol dehydrogenase-2 (ADH2) and aldehyde
dehydrogenase-2 (ALDH2) polymorphisms on esophageal cancer susceptibility in …

Ethanol cytotoxic effect on trophoblast cells

S Clave, X Joya, J Salat-Batlle, O Garcia-Algar, O Vall - Toxicology letters, 2014 - Elsevier
Prenatal ethanol exposure may cause both, altered fetal neurodevelopment and impaired
placental function. These disturbances can lead to growth retardation, which is one of the …

Smoking, drinking, and pancreatitis: a population-based cohort study in Taiwan

HH Lin, HY Chang, YT Chiang, MS Wu, JT Lin… - Pancreas, 2014 - journals.lww.com
Objectives In Western population, smoking is a dose-dependent risk factor for pancreatitis,
whereas a threshold of 5 drinks per day may exist for alcohol to increase pancreatitis risk …

Distribution of ADH1B, ALDH2, CYP2E1∗ 6, and CYP2E1∗ 7B genotypes in Turkish population

Z Kayaaltı, T Söylemezoğlu - Alcohol, 2010 - Elsevier
The most well-known metabolic pathways from ethanol to acetaldehyde include alcohol
dehydrogenase (ADH) and the microsomal ethanol oxidizing system that involves …

Rare Alleles within the CYP2E1 (MEOS System) Could be Associated with Better Short‐Term Health Outcome after Acute Methanol Poisoning

JA Hubacek, D Pelclova, Z Seidl… - Basic & Clinical …, 2015 - Wiley Online Library
Genetic polymorphisms influence the metabolism of ethanol and methanol, but the potential
effects of genetic predisposition on the clinical course, outcome and short‐term health …