A molecular probe for the detection of polar lipids in live cells
Lipids have an important role in many aspects of cell biology, including membrane
architecture/compartment formation, intracellular traffic, signalling, hormone regulation …
architecture/compartment formation, intracellular traffic, signalling, hormone regulation …
Exploiting directed self-assembly and disassembly for off-to-on fluorescence responsive live cell imaging
N Curtin, M Garre, JB Bodin, N Solem… - RSC …, 2022 - pubs.rsc.org
A bio-responsive nanoparticle was formed by the directed self-assembly (DSA) of a
hydrophobic NIR-fluorophore with poloxamer P188. Fluorophore emission was switched off …
hydrophobic NIR-fluorophore with poloxamer P188. Fluorophore emission was switched off …
Skeletal muscle fiber type-selective effects of acute exercise on insulin-stimulated glucose uptake in insulin-resistant, high-fat-fed rats
Insulin-stimulated glucose uptake (GU) by skeletal muscle is enhanced several hours after
acute exercise in rats with normal or reduced insulin sensitivity. Skeletal muscle is …
acute exercise in rats with normal or reduced insulin sensitivity. Skeletal muscle is …
Luminescent metal complexes as emerging tools for lipid imaging
BJ Schwehr, D Hartnell, M Massi… - … Ligand Chromophores for …, 2022 - Springer
Fluorescence microscopy is a key tool in the biological sciences, which finds use as a
routine laboratory technique (eg, epifluorescence microscope) or more advanced confocal …
routine laboratory technique (eg, epifluorescence microscope) or more advanced confocal …
Mitochondrial carnitine palmitoyltransferase 2 is involved in Nε-(carboxymethyl)-lysine-mediated diabetic nephropathy
J Lee, JY Hyon, JY Min, YH Huh, HJ Kim, H Lee… - Pharmacological …, 2020 - Elsevier
Diabetic nephropathy (DN) is the most common cause of end-stage renal disease in the
world. Advanced glycation end products (AGEs) are thought to be involved in the …
world. Advanced glycation end products (AGEs) are thought to be involved in the …
A guide to studying human dermal adipocytes in situ
C Nicu, J Pople, L Bonsell, R Bhogal… - Experimental …, 2018 - Wiley Online Library
Dermal white adipose tissue (DWAT) is a main component of human skin, composed of
individual lipid‐laden mesenchymal cells known as dermal adipocytes (DA s). Besides their …
individual lipid‐laden mesenchymal cells known as dermal adipocytes (DA s). Besides their …
Adiponectin regulates aquaglyceroporin expression in hepatic stellate cells altering their functional state
M Tardelli, V Moreno‐Viedma, M Zeyda… - Journal of …, 2017 - Wiley Online Library
Abstract Background and Aim Obesity is a major risk factor for liver fibrosis and tightly
associated with low levels of adiponectin. Adiponectin has antifibrogenic activity protecting …
associated with low levels of adiponectin. Adiponectin has antifibrogenic activity protecting …
Chemical imaging of lipid droplets in muscle tissues using hyperspectral coherent Raman microscopy
The accumulation of lipids in non-adipose tissues is attracting increasing attention due to its
correlation with obesity. In muscle tissue, ectopic deposition of specific lipids is further …
correlation with obesity. In muscle tissue, ectopic deposition of specific lipids is further …
Nile Red Quantifier: a novel and quantitative tool to study lipid accumulation in patient-derived circulating monocytes using confocal microscopy
JG Schnitzler, SJB Moens, F Tiessens, GJ Bakker… - Journal of lipid …, 2017 - ASBMB
The inflammatory profile of circulating monocytes is an important biomarker for
atherosclerotic plaque vulnerability. Recent research revealed that peripheral lipid uptake …
atherosclerotic plaque vulnerability. Recent research revealed that peripheral lipid uptake …
BRCA1 is a novel regulator of metabolic function in skeletal muscle
KC Jackson, EK Gidlund, J Norrbom, AP Valencia… - Journal of lipid …, 2014 - ASBMB
Breast cancer type 1 (BRCA1) susceptibility protein is expressed across multiple tissues
including skeletal muscle. The overall objective of this investigation was to define a …
including skeletal muscle. The overall objective of this investigation was to define a …