Disruptions of ovarian function in women are associated with increased risk of metabolic
disease due to dysregulation of peripheral glucose homeostasis in skeletal muscle. Our …

Obesity is characterized by an excessive triacylglycerol accumulation in white adipocytes.
Various mechanisms allowing the tight regulation of triacylglycerol storage and mobilization …

Purpose In recent years, the increasing consumption of soft drinks containing high-fructose
corn syrup or sucrose has caused a rise in fructose intake, which has been related to the …

Despite over 50 years of research, a comprehensive understanding of how intramuscular
triglyceride (IMTG) is stored in skeletal muscle and its contribution as a fuel during exercise …

Simple Summary Biological evolution implies fitness of newly evolved organisms that have
inherent adaptive traits because of mutations in genes. However, most mutations are …

Abstract Kidney cancer accounts for 2.5% of all cancers, with an annual global incidence of
almost 300,000 cases leading to 111,000 deaths. Approximately 85% of kidney tumors are …

Brown adipose tissue (BAT) plays a key role in energy expenditure and heat generation and
is a promising target for diagnosing and treating obesity, diabetes and related metabolism …

A series of benzoxazole-pyridinium salt derivatives with two-photon excited fluorescence
performance were synthesized and fully characterized. Among them, compounds 2, 3 and 4 …

Autophagy activation has the potential to ameliorate neurodegenerative disease
phenotypes, including protein aggregation, lipid level perturbations and axonal trafficking …

Ubiquitin C-terminal hydrolase L1 (UCHL1) is a deubiquitinating enzyme that was originally
found in neurons. We found that UCHL1 is highly expressed in slow oxidative skeletal …