The transient receptor potential melastatin‐2 (TRPM2) channel belongs to the transient
receptor potential channel superfamily and is a cation channel permeable to Na+ and Ca …

Since a negative calcium balance is present in spontaneously hypertensive rats, we
searched for the gene (s) involved in this dysregulation. A cDNA library was constructed …

Introduction: Nitric oxide (NO), synthesized from l-arginine by the enzyme nitric oxide
synthase (NOS), seems to play an ambiguous role during tissue ischemia–reperfusion …

Neonatal nephron loss may follow hypoxic-ischemic events or nephrotoxic medications. Its
long-term effects on the kidney are still unclear. Unlike term infants, preterm neonates less …

While unilateral nephrectomy (UNx) is suggested to protect against ischemia-reperfusion
injury (IRI) in the remaining kidney, the mechanisms underlying this protection remain to be …

Abstract Background (Pro) renin receptor [(P) RR], a trans-membrane receptor for renin and
prorenin, is involved in the local activation of renin–angiotensin system (RAS) in the kidney …

Although chronic cardiac dysfunction is known to progressively exacerbate renal injury, a
condition known as type 2 cardiorenal syndrome (CRS), the mechanism responsible is …

Objective To evaluate the effects of l‐arginine, a nitric oxide donor, on kidney levels of
malondialdehyde (MDA, a product of cellular lipid peroxidation), serum creatinine levels …

Background. Previous studies showed that unilateral renal damage is attenuated by prior
contralateral uninephrectomy (Nx) in ischaemia‐induced acute renal failure (ARF). Since …

Uninephrectomy (Unx) is followed by the compensatory renal growth (CRG) of the remaining
kidney. Previous evidence has shown that during CRG, renal tissue is resistant to a variety …