Evaluation of the new continuous mononuclear cell collection protocol versus an older version on two different apheresis machines
S Spoerl, D Wäscher, S Nagel, C Peschel… - …, 2018 - Wiley Online Library
BACKGROUND Cell separators are routinely used to collect CD34+ blood stem cells in the
context of customized stem cell transplantation procedures. The Spectra Optia (Terumo …
context of customized stem cell transplantation procedures. The Spectra Optia (Terumo …
Continuous Mononuclear Cell Collection (cMNC) protocol impact on hematopoietic stem cell collections in donors with negative collection predictors
K Bartnik, M Maciejewska, R Farhan… - … and Apheresis Science, 2018 - Elsevier
Background Recently, novel protocol utilizing Continuous Mononuclear Cell Collection
(cMNC) have been introduced for leukapheresis. We compared the efficacy of cMNC with an …
(cMNC) have been introduced for leukapheresis. We compared the efficacy of cMNC with an …
Comparison of the CMNC and MNC apheresis protocol for the collection of T‐cells showed comparable outcome: an observational study in a single centre
D Putensen, R Smith, L Pilcher… - Journal of Clinical …, 2018 - Wiley Online Library
Background An increasing demand for human lymphocytes require an efficient, reliable and
reproducible lymphocyte process. Here, we compare the Spectra Optia® CMNC protocol …
reproducible lymphocyte process. Here, we compare the Spectra Optia® CMNC protocol …
Prediction of blood volume to be processed to achieve a target number of CD34+ cells: Development, validation and implementation of a formula
I García‐García, J Cid, G Moreno‐Jiménez… - Vox …, 2023 - Wiley Online Library
Abstract Background and Objectives Calculation of blood volume (BV) to be processed to
achieve the target number of CD34+ cells can be accomplished by using collection …
achieve the target number of CD34+ cells can be accomplished by using collection …
Low-volume leukapheresis in non-cytokine-stimulated donors for the collection of mononuclear cells
A Anyanwu, N Sitzmann, S Hetjens, H Klüter… - Transfusion Medicine …, 2018 - karger.com
Background: There is an increasing demand for products containing mononuclear cells
(MNCs) for cellular immune therapy. Hence, leukapheresis is increasingly performed in …
(MNCs) for cellular immune therapy. Hence, leukapheresis is increasingly performed in …
S pectra O ptia granulocyte apheresis collections result in higher collection efficiency of viable, functional neutrophils in a randomized, crossover, multicenter trial
JA Cancelas, A Padmanabhan, T Le, DR Ambruso… - …, 2015 - Wiley Online Library
Background Granulocyte transfusion from healthy donors is used in the treatment of patients
with granulocyte function defects, or transient neutropenia and severe bacterial or fungal …
with granulocyte function defects, or transient neutropenia and severe bacterial or fungal …
Evaluation of the spectra Optia® mononuclear cell collection procedure in multiple myeloma patients
G Long, EK Waller, S Gregurek, G Tricot… - Journal of clinical …, 2015 - Wiley Online Library
Background: Peripheral blood stem cell (PBSC) rescue following myeloablative therapy is a
mainstay of cancer therapy. To evaluate the ability of the Spectra Optia Apheresis System …
mainstay of cancer therapy. To evaluate the ability of the Spectra Optia Apheresis System …
Comparison of two apheresis systems during hematopoietic progenitor stem cell collections at a tertiary medical center
BACKGROUND The Spectra Optia is a newer apheresis system developed based on the
COBE Spectra platform. COBE Spectra requires more manual control, while Spectra Optia …
COBE Spectra platform. COBE Spectra requires more manual control, while Spectra Optia …
Prospective randomized and crossover comparison of two apheresis machines for peripheral blood stem cell collection: a multicenter study
K Ikeda, K Minakawa, K Muroi, S Fujiwara… - …, 2016 - Wiley Online Library
BACKGROUND Improving apheresis technology may lead to an efficient and safe
peripheral blood stem cell (PBSC) collection. Recently, the Spectra Optia (Optia, Terumo …
peripheral blood stem cell (PBSC) collection. Recently, the Spectra Optia (Optia, Terumo …
Human bone marrow processing using a new continuous‐flow cell separation device
MG Guttridge, C Bailey, C Sidders, J Nichols… - …, 2016 - Wiley Online Library
BACKGROUND Processing of bone marrow (BM) is often required to remove incompatible
red blood cells (RBCs) or to reduce the volume before transplantation or cryopreservation …
red blood cells (RBCs) or to reduce the volume before transplantation or cryopreservation …