BACKGROUND Cell separators are routinely used to collect CD34+ blood stem cells in the
context of customized stem cell transplantation procedures. The Spectra Optia (Terumo …

Background Recently, novel protocol utilizing Continuous Mononuclear Cell Collection
(cMNC) have been introduced for leukapheresis. We compared the efficacy of cMNC with an …

Background An increasing demand for human lymphocytes require an efficient, reliable and
reproducible lymphocyte process. Here, we compare the Spectra Optia® CMNC protocol …

Abstract Background and Objectives Calculation of blood volume (BV) to be processed to
achieve the target number of CD34+ cells can be accomplished by using collection …

Background: There is an increasing demand for products containing mononuclear cells
(MNCs) for cellular immune therapy. Hence, leukapheresis is increasingly performed in …

Background Granulocyte transfusion from healthy donors is used in the treatment of patients
with granulocyte function defects, or transient neutropenia and severe bacterial or fungal …

Background: Peripheral blood stem cell (PBSC) rescue following myeloablative therapy is a
mainstay of cancer therapy. To evaluate the ability of the Spectra Optia Apheresis System …

BACKGROUND The Spectra Optia is a newer apheresis system developed based on the
COBE Spectra platform. COBE Spectra requires more manual control, while Spectra Optia …

BACKGROUND Improving apheresis technology may lead to an efficient and safe
peripheral blood stem cell (PBSC) collection. Recently, the Spectra Optia (Optia, Terumo …

BACKGROUND Processing of bone marrow (BM) is often required to remove incompatible
red blood cells (RBCs) or to reduce the volume before transplantation or cryopreservation …