Cellular immunity in ASFV responses

HH Takamatsu, MS Denyer, A Lacasta, CMA Stirling… - Virus research, 2013 - Elsevier
African swine fever virus (ASFV) infection usually results in an acute haemorrhagic disease
with a mortality rate approaching 100% in domestic pigs. However, pigs can survive …

Immunoregulatory role of NK cells in tissue inflammation and regeneration

A Tosello-Trampont, FA Surette, SE Ewald… - Frontiers in …, 2017 - frontiersin.org
NK cells represent an important first line of defense against viral infection and cancer and
are also involved in tissue homeostasis. Studies of NK cell activation in the last decade have …

[PDF][PDF] Sorafenib induces pyroptosis in macrophages and triggers natural killer cell–mediated cytotoxicity against hepatocellular carcinoma

C Hage, S Hoves, L Strauss, S Bissinger, Y Prinz… - …, 2019 - Wiley Online Library
Antiangiogenic and cytotoxic effects are considered the principal mechanisms of action of
sorafenib, a multitarget kinase inhibitor approved for the treatment of hepatocellular …

Cytokine storm in domestic pigs induced by infection of virulent African swine fever virus

S Wang, J Zhang, Y Zhang, J Yang, L Wang… - Frontiers in veterinary …, 2021 - frontiersin.org
African swine fever, caused by African swine fever virus (ASFV), is a highly contagious
hemorrhagic disease of domestic pigs. The current continent-wide pandemic has persisted …

Hepatitis C virus–induced myeloid-derived suppressor cells suppress NK cell IFN-γ production by altering cellular metabolism via arginase-1

CC Goh, KM Roggerson, HC Lee… - The journal of …, 2016 - journals.aai.org
The hepatitis C virus (HCV) infects∼ 200 million people worldwide. The majority of infected
individuals develop persistent infection, resulting in chronic inflammation and liver disease …

Host responses to live-attenuated ASFV (HLJ/18–7GD)

Y Fan, W Chen, C Jiang, X Zhang, Y Sun, R Liu… - Viruses, 2022 - mdpi.com
African swine fever (ASF) is a highly contagious and fatal disease caused by the African
swine fever virus. Recently, the multigene family and CD2v gene-deleted ASF vaccine …

[HTML][HTML] Progress in the development of vaccines for hepatitis C virus infection

F Ghasemi, S Rostami, Z Meshkat - World journal of …, 2015 - ncbi.nlm.nih.gov
The hepatitis C virus (HCV), first described in 1989, is now a leading cause of liver cirrhosis
and hepatocellular carcinoma. With more than 170 million people infected globally, this virus …

[HTML][HTML] Role of relevant immune-modulators and cytokines in hepatocellular carcinoma and premalignant hepatic lesions

ARN Zekri, S El Deeb, AA Bahnassy… - World Journal of …, 2018 - ncbi.nlm.nih.gov
AIM To assess the levels of different immune modulators in patients with hepatocellular
carcinoma (HCC), in relation to other hepatic diseases. METHODS Eighty-eight patients …

Association of killer cell immunoglobulin‐like receptors with spontaneous clearance of hepatitis C virus in the Chinese population

Z Shan, J Huang, Q Liao, K Huang, M Wang, R Xu… - …, 2018 - Wiley Online Library
BACKGROUND Natural killer (NK) cells are critical components in innate immune response
to viral infection. Killer cell immunoglobulin‐like receptors (KIRs) are involved in regulating …

Highly differential count of circulating and tumor infiltrating immune cells in patients with non-HCV/non-HBV hepatocellular carcinoma

MB Schoenberg, T Zhu, J Hao, JN Bucher, X Li… - Cancer Immunology …, 2022 - Springer
Background Liver transplantation and liver resection are curative options for early
hepatocellular carcinoma (HCC). The outcome is in part depended on the immunological …