Diabetes mellitus comprises a group of carbohydrate metabolism disorders that share a
common main feature of chronic hyperglycemia that results from defects of insulin secretion …

In a diabetic milieu high levels of reactive oxygen species (ROS) are induced. This
contributes to the vascular complications of diabetes. Recent studies have shown that ROS …

The mechanisms underlying innate immune memory have been extensively explored in the
last decades but are in fact largely unknown. Although the specificity of adaptive immune …

Endothelial cells (ECs) are more than inert blood vessel lining material. Instead, they are
active players in the formation of new blood vessels (angiogenesis) both in health and (life …

Abstract The Metabolic Syndrome is a cluster of cardio‐metabolic risk factors and
comorbidities conveying high risk of both cardiovascular disease and type 2 diabetes. It is …

The Mediterranean diet (MedDiet) is one of the most widely described and evaluated dietary
patterns in scientific literature. It is characterized by high intakes of vegetables, legumes …

Oxidative stress occurs whenever the release of reactive oxygen species (ROS) exceeds
endogenous antioxidant capacity. In this paper, we review the specific role of several …

Aim and objective Emerging translational evidence suggests that epigenetic alterations
(DNA methylation, miRNA expression, and histone modifications) occur after external stimuli …

Significance: A growing body of clinical and experimental evidence has challenged the
traditional understanding that only the adaptive immune system can mount immunological …

Atherosclerosis is the narrowing of arteries due to the accumulation of macrophages
overloaded with lipids resulting in foam cell formation, and these events occur preferentially …