Fezolinetant in the treatment of vasomotor symptoms associated with menopause

H Depypere, C Lademacher, E Siddiqui… - Expert Opinion on …, 2021 - Taylor & Francis
Introduction: Although international clinical practice guidelines recognize a continued role
for menopausal hormone therapy (HT), particularly for symptomatic women< 60 years of age …

Fezolinetant: first approval

A Lee - Drugs, 2023 - Springer
Fezolinetant (VEOZAH™) is an oral, small molecule, neurokinin 3 receptor (NK3R)
antagonist, which is being developed by Astellas Pharma Inc. for the treatment of moderate …

Are novel treatments for brain disorders hiding in plain sight?

L Duncan, K Deisseroth - Neuropsychopharmacology, 2024 - nature.com
Psychiatric diseases are strongly influenced by genetics, but genetically guided treatments
have been slow to develop, and precise molecular mechanisms remain mysterious …

[HTML][HTML] Neurokinin 1/3 receptor antagonists for menopausal women: A current systematic review and insights into the investigational non-hormonal therapy

F Hassan, A Saleem, SS Samuel, Z Sarfraz, A Sarfraz… - Medicine, 2023 - journals.lww.com
Background: Over 75% of menopausal women experience vasomotor symptoms (VMS),
such as night sweats and hot flashes. Despite the prevalence of these symptoms, there is …

Systematic review and network meta-analysis comparing the efficacy of fezolinetant with hormone and nonhormone therapies for treatment of vasomotor symptoms …

A Morga, M Ajmera, E Gao, O Patterson-Lomba… - Menopause, 2024 - journals.lww.com
Systematic review and network meta-analysis comparing the ef... : Menopause Systematic
review and network meta-analysis comparing the efficacy of fezolinetant with hormone and …

[HTML][HTML] Potential oestrogenic effects (following the OECD test guideline 440) and thyroid dysfunction induced by pure cyanotoxins (microcystin-LR …

A Casas-Rodríguez, R Moyano… - Environmental …, 2023 - Elsevier
Potential endocrine-disrupting properties of cyanotoxins, such as microcystin-LR (MC-LR)
and cylindrospermopsin (CYN) are of concern due to their increasing occurrence, the …

Fezolinetant for the treatment of vasomotor symptoms associated with menopause: a meta-analysis

MP Chavez, E Pasqualotto, ROM Ferreira, A Hohl… - …, 2024 - Taylor & Francis
This systematic review and meta-analysis investigated the efficacy and safety of fezolinetant
for the treatment of moderate-to-severe vasomotor symptoms (VMS) associated with …

Effectiveness and safety of fezolinetant in alleviating vasomotor symptoms linked to Menopause.: A systematic review and Meta-Analysis

AAA Elnaga, MA Alsaied, AM Elettreby… - European Journal of …, 2024 - Elsevier
Abstract Background & Objective Vasomotor symptoms (VMS) are the most common
symptoms during menopause including hot flushes and night sweats. They are highly …

Menopausal symptom management: Fezolinetant's varied doses provide effective relief for vasomotor symptoms in women-A meta-analysis of 3291 participants.

AM Elhusein, HA Fadlalmola… - African Journal of …, 2024 - search.ebscohost.com
Menopause represents the physiological transition when a woman's reproductive period
ends associated with a variety of symptoms, including vasomotor symptoms, such as night …

Efficacy and safety of fezolinetant for moderate to severe vasomotor symptoms associated with menopause among women in East Asia: a phase 3 randomized study …

X Ruan, W Bai, M Ren, T Kim, JY Lee… - Journal of …, 2024 - journals.sagepub.com
Objective To evaluate the efficacy and safety of fezolinetant for moderate to severe
vasomotor symptoms (VMS) associated with menopause in East Asian women. Methods In …