[HTML][HTML] Stem cell-derived exosomes: emerging therapeutic opportunities for wound healing

C Zhou, B Zhang, Y Yang, Q Jiang, T Li, J Gong… - Stem cell research & …, 2023 - Springer
Wound healing is a dynamic and highly sequential process involving a series of overlapping
spatial and temporal phases, including hemostasis, inflammation, proliferation, and tissue …

[HTML][HTML] Biomechanical regulatory factors and therapeutic targets in keloid fibrosis

F Feng, M Liu, L Pan, J Wu, C Wang, L Yang… - Frontiers in …, 2022 - frontiersin.org
Keloids are fibroproliferative skin disorder caused by abnormal healing of injured or irritated
skin and are characterized by excessive extracellular matrix (ECM) synthesis and …

Activating transcription factor 3 (ATF3) regulates cell growth, apoptosis, invasion and collagen synthesis in keloid fibroblast through transforming growth factor beta …

XM Wang, XM Liu, Y Wang, ZY Chen - Bioengineered, 2021 - Taylor & Francis
The successful treatment of keloids is a great challenge in the plastic surgery field. Activating
transcription factor 3 (ATF3) is discovered as an adaptive responsive gene, which plays a …

Keloid: genetic susceptibility and contributions of genetics and epigenetics to its pathogenesis

S Liu, H Yang, J Song, Y Zhang… - Experimental …, 2022 - Wiley Online Library
Keloid, characterized by fibroproliferative disorders of the skin, can be developed in people
of different genders, ages and ethnicities. Keloid can appear in any part of the body but are …

Diagnosis and management in Rubinstein-Taybi syndrome: first international consensus statement

D Lacombe, A Bloch-Zupan, C Bredrup… - Journal of medical …, 2024 - jmg.bmj.com
Rubinstein-Taybi syndrome (RTS) is an archetypical genetic syndrome that is characterised
by intellectual disability, well-defined facial features, distal limb anomalies and atypical …

Mechanisms underlying pathological scarring by fibroblasts during wound healing

Y Ma, Z Liu, LL Miao, X Jiang, H Ruan… - International Wound …, 2023 - Wiley Online Library
Pathological scarring is an abnormal outcome of wound healing, which often manifests as
excessive proliferation and transdifferentiation of fibroblasts (FBs), and excessive deposition …

Adipose‐derived mesenchymal stem cells‐sourced exosomal micro RNA‐7846‐3p suppresses proliferation and pro‐angiogenic role of keloid fibroblasts by …

D Wu, X Liu, Z Jin - Journal of Cosmetic Dermatology, 2023 - Wiley Online Library
Abstract Background Exosomes (Exos) and their contained microRNAs (miRNAs) have
been emergingly recognized as key regulators in spanning biological processes, including …

Non-coding RNAs in hypertrophic scars and keloids: Current research and clinical relevance: A review

L Su, J Han - International Journal of Biological Macromolecules, 2023 - Elsevier
Hypertrophic scars (HS) and keloids (KD) are lesions that develop as a result of excessive
fibroblast proliferation and collagen deposition in response to dermal injury, leading to …

[HTML][HTML] Emerging roles of interactions between ncRNAs and other epigenetic modifications in breast cancer

J Xie, L Gan, B Xue, X Wang, X Pei - Frontiers in Oncology, 2023 - frontiersin.org
Up till the present moment, breast cancer is still the leading cause of cancer-related death in
women worldwide. Although the treatment methods and protocols for breast cancer are …

[HTML][HTML] Targeting Wnt/β-catenin signaling and its interplay with TGF-β and Notch signaling pathways for the treatment of chronic wounds

DB Gumede, H Abrahamse, NN Houreld - Cell Communication and …, 2024 - Springer
Wound healing is a tightly regulated process that ensures tissue repair and normal function
following injury. It is modulated by activation of pathways such as the transforming growth …